PXD046207-1

PXD046207 is an original dataset announced via ProteomeXchange.

Title	TMT-based proteomics analysis of optic nerve lysates from oligodendrocyte-specific Kir4.1 knockout mice
Description	To study the role oligodendroglial Kir4.1 in regulating axonal energy metabolism, oligodendrocyte-specific Kir4.1 knockout mice and their littermate controls were used; optic nerve lysates were prepared for subsequent TMT-based proteomics.
HostingRepository	PRIDE
AnnounceDate	2024-01-30
AnnouncementXML	Submission_2024-01-30_08:43:44.941.xml
DigitalObjectIdentifier
ReviewLevel	Peer-reviewed dataset
DatasetOrigin	Original dataset
RepositorySupport	Unsupported dataset by repository
PrimarySubmitter	Aiman Saab
SpeciesList	scientific name: Mus musculus (Mouse); NCBI TaxID: 10090;
ModificationList	TMT6plex-126 reporter+balance reagent acylated residue; acetylated residue; iodoacetamide derivatized residue
Instrument	Orbitrap Fusion Lumos

Revision	Datetime	Status	ChangeLog Entry
0	2023-10-18 05:48:05	ID requested
⏵ 1	2024-01-30 08:43:45	announced
2	2024-10-22 06:28:05	announced	2024-10-22: Updated project metadata.

10.1038/S41593-023-01558-3;

submitter keyword: LC-MSMS,Mouse, TMT proteomics, optic nerve, oligodendrocytes, Kir4.1 knockout

Aiman Saab
contact affiliation	Institute of Pharmacology and Toxicology, University of Zurich, Switzerland
contact email	asaab@pharma.uzh.ch
lab head
Aiman Saab
contact affiliation	University of Zurich, Institute of Pharmacology & Toxicology
contact email	asaab@pharma.uzh.ch
dataset submitter

Dataset FTP location NOTE: Most web browsers have now discontinued native support for FTP access within the browser window. But you can usually install another FTP app (we recommend FileZilla) and configure your browser to launch the external application when you click on this FTP link. Or otherwise, launch an app that supports FTP (like FileZilla) and use this address: ftp://ftp.pride.ebi.ac.uk/pride/data/archive/2024/01/PXD046207

PRIDE project URI

• PRIDE
  1. PXD046207
     1. Label: PRIDE project
     2. Name: TMT-based proteomics analysis of optic nerve lysates from oligodendrocyte-specific Kir4.1 knockout mice