PXD046081-1

PXD046081 is an original dataset announced via ProteomeXchange.

Title	Investigating the impact of SopB on the gut epithelium – proteome and phosphoproteome
Description	In this study, the impact of the Salmonella SPI1 effector SopB on the gut epithelium was investigated based on a proteome and a phosphoproteome.
HostingRepository	PRIDE
AnnounceDate	2026-07-07
AnnouncementXML	Submission_2026-07-07_07:11:06.507.xml
DigitalObjectIdentifier	https://doi.org/10.6019/PXD046081
ReviewLevel	Peer-reviewed dataset
DatasetOrigin	Original dataset
RepositorySupport	Supported dataset by repository
PrimarySubmitter	Kristin Schubert
SpeciesList	scientific name: Mus musculus (Mouse); NCBI TaxID: NEWT:10090;
ModificationList	phosphorylation to amine thiol; iodoacetamide derivatized residue
Instrument	Q Exactive HF

Revision	Datetime	Status	ChangeLog Entry
0	2023-10-12 01:55:34	ID requested
⏵ 1	2026-07-07 07:11:07	announced

10.6019/PXD046081;

10.1038/s41467-026-74942-9;

Diab N, Yong CH, Stange EL, Birk MS, Schmitz MA, D, ü, sterh, ö, ft S, Pes J, Ferle KN, Karkossa I, Schubert K, Deiwick J, Vucur M, Luedde T, Torow N, Ludwig A, Dupont A, Selkrig J, von Bergen M, Hensel M, Zhang K, Hornef MW, Salmonella SopB suppresses post-transcriptionally regulated cytokine release to reduce early tissue inflammation and delay disease progression. Nat Commun, 17(1):(2026) [pubmed]

submitter keyword: salmonella, phosphoproteome, SopB, mice, LFQ, M-ICcl2, proteome

Kristin Schubert
contact affiliation	Helmholtz-Centre for Environmental Research – UFZ
contact email	kristin.schubert@ufz.de
lab head
Kristin Schubert
contact affiliation	Brandenburg University of Technology Cottbus-Senftenberg
contact email	kristin.schubert@ufz.de
dataset submitter

Dataset FTP location NOTE: Most web browsers have now discontinued native support for FTP access within the browser window. But you can usually install another FTP app (we recommend FileZilla) and configure your browser to launch the external application when you click on this FTP link. Or otherwise, launch an app that supports FTP (like FileZilla) and use this address: ftp://ftp.pride.ebi.ac.uk/pride/data/archive/2026/07/PXD046081

PRIDE project URI

• PRIDE
  1. PXD046081
     1. Label: PRIDE project
     2. Name: Investigating the impact of SopB on the gut epithelium – proteome and phosphoproteome