PXD045973-1
PXD045973 is an original dataset announced via ProteomeXchange.
Dataset Summary
Title | Proteomic investigation on the direct corona of nanoparticles |
Description | The application of nanotechnology to medicine has gained wide attention in numerous important scientific fields, ranging from diagnostic imaging with contrast agents to targeted drug delivery and photodynamic therapy.However, upon contact with biological fluid, these GNPs are coated with a layer/corona of proteins that leads to unexpected changes in cellular uptake, cellular interactions, biodistribution, and nanotoxicity. Therefore, detailed knowledge of the protein corona is of importance for the designation and development of nanoparticles with high targeting effect. |
HostingRepository | iProX |
AnnounceDate | 2023-10-08 |
AnnouncementXML | Submission_2023-10-08_19:49:17.008.xml |
DigitalObjectIdentifier | |
ReviewLevel | Peer-reviewed dataset |
DatasetOrigin | Original dataset |
RepositorySupport | Unsupported dataset by repository |
PrimarySubmitter | Jian Zhou |
SpeciesList | scientific name: Homo sapiens; NCBI TaxID: 9606; |
ModificationList | iodoacetamide derivatized residue; monohydroxylated residue |
Instrument | TripleTOF 5600 |
Dataset History
Revision | Datetime | Status | ChangeLog Entry |
---|---|---|---|
0 | 2023-10-08 19:49:07 | ID requested | |
⏵ 1 | 2023-10-08 19:49:17 | announced |
Publication List
Dataset with its publication pending |
Keyword List
submitter keyword: nanoparticle, protein corona, proteomics, mass spectrometry |
Contact List
Jian Zhou | |
---|---|
contact affiliation | Chongqing Medical University |
contact email | zhoujian@cqmu.edu.cn |
lab head | |
Jian Zhou | |
contact affiliation | Chongqing Medical University |
contact email | zhoujian@cqmu.edu.cn |
dataset submitter |
Full Dataset Link List
iProX dataset URI |