PXD045846-1

PXD045846 is an original dataset announced via ProteomeXchange.

Dataset Summary

Title	Forebrain Eml1 depletion reveals early centrosomal dysfunction causing subcortical heterotopia
Description	The layered structure of the cerebral cortex is formed through a complicated sequence of highly controlled stages during corticogenesis. The perturbation of neuronal migration and cell division during this process can result a rare disorder called as cortical heterotopia. EML1 is a heterotopia associated gene where the perturbations cause heterotopia formation in human as well as in mouse. To elaborate on the EML1 interactome and its disruptions by heterotopia-associated mutation, we performed BioID proximity labeling of EML1 and EML1*T243A, a human SH-associated mutant form of the protein.
HostingRepository	PRIDE
AnnounceDate	2024-08-26
AnnouncementXML	Submission_2024-08-26_02:32:32.153.xml
DigitalObjectIdentifier
ReviewLevel	Peer-reviewed dataset
DatasetOrigin	Original dataset
RepositorySupport	Unsupported dataset by repository
PrimarySubmitter	Berfu Nur Yiğit
SpeciesList	scientific name: Mus musculus (Mouse); NCBI TaxID: 10090;
ModificationList	iodoacetamide derivatized residue
Instrument	Q Exactive

Dataset History

Revision	Datetime	Status	ChangeLog Entry
0	2023-10-02 04:17:31	ID requested
⏵ 1	2024-08-26 02:32:32	announced
2	2024-10-22 06:56:31	announced	2024-10-22: Updated project metadata.

Publication List

10.1083/JCB.202310157;

10.1083/JCB.202310157;

Keyword List

submitter keyword: Cell Line,Mouse, BioID, EML1

submitter keyword: Cell Line,Mouse, BioID, EML1

Contact List

Prof. Dr.
contact affiliation	Koc University
contact email	nozlu@ku.edu.tr
lab head
Berfu Nur Yiğit
contact affiliation	Koc University
contact email	byigit19@ku.edu.tr
dataset submitter

Full Dataset Link List

Dataset FTP location NOTE: Most web browsers have now discontinued native support for FTP access within the browser window. But you can usually install another FTP app (we recommend FileZilla) and configure your browser to launch the external application when you click on this FTP link. Or otherwise, launch an app that supports FTP (like FileZilla) and use this address: ftp://ftp.pride.ebi.ac.uk/pride/data/archive/2024/08/PXD045846
PRIDE project URI

Dataset FTP location
NOTE: Most web browsers have now discontinued native support for FTP access within the browser window. But you can usually install another FTP app (we recommend FileZilla) and configure your browser to launch the external application when you click on this FTP link. Or otherwise, launch an app that supports FTP (like FileZilla) and use this address: ftp://ftp.pride.ebi.ac.uk/pride/data/archive/2024/08/PXD045846

PRIDE project URI

Repository Record List

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