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PXD045568 is an original dataset announced via ProteomeXchange.

Dataset Summary
TitleIn-Gel digest and filter-aided sample preparation to identify Dermatophagoides - and yeast protein antigens in severe equine asthma.
DescriptionSevere equine asthma (SEA) is a common, chronic respiratory disease of horses characterized by hyperreactivity to hay dust which has many similarities to severe neutrophilic asthma in humans. A 2D immunoblot approach was used to identify quantitative differences in the recognition of the two-dimensional gel electrophoresis (2-DE) pattern between asthmatic and helthy horses´sera. Differentially regulated spots were cut from a 2-D gel and used for in-gel digestion followed by LC-MS to identify possible antigens.
ReviewLevelPeer-reviewed dataset
DatasetOriginOriginal dataset
RepositorySupportSupported dataset by repository
PrimarySubmitterDaniela Volke
SpeciesList scientific name: Saccharomyces cerevisiae; NCBI TaxID: 4932; scientific name: Dermatophagoides pteronyssinus; NCBI TaxID: 6956;
ModificationListCarbamidomethyl; Oxidation
InstrumentSYNAPT G2-Si
Dataset History
RevisionDatetimeStatusChangeLog Entry
02023-09-21 11:18:18ID requested
12023-11-30 14:09:01announced
22024-01-26 17:05:20announced: Added PubMed Id
Publication List
Schnabel CL, Jentsch MC, L, ü, bke S, Kaiser-Thom S, Gerber V, Vrtala S, Huang HJ, Rhyner C, Wagner B, Hoffmann R, Volke D, and yeast protein antigens in severe equine asthma in a preliminary study. Front Immunol, 14():1293684(2023) [pubmed]
Keyword List
submitter keyword: Immunoglobulin isotypes, proteomics, 2D immunoblot, LC-MS, asthma, COPD, RAO, heaves
Contact List
Ralf Hoffmann
contact affiliationUniversität Leipzig/BBZ
contact emailralf.hoffmann@bbz.uni-leipzig.de
lab head
Daniela Volke
contact affiliationUniversität Leipzig/BBZ
contact emaildaniela.volke@bbz.uni-leipzig.de
dataset submitter
Full Dataset Link List
Panorama Public dataset URI