PXD045508-1

PXD045508 is an original dataset announced via ProteomeXchange.

Title	Immune cell proteomes of Long COVID patients have functional changes similar to those in Myalgic Encephalomyelitis/Chronic Fatigue Syndrome.
Description	To investigate the pathophysiology of Long COVID (LC), a pilot study of patients and healthy controls has used quantitative proteomics to discover changes in peripheral blood mononuclear cell (PBMC) proteoms. The proteomes of LC patients and healthy controls were analysed by Sequential Window Acquisition of all Theoretical Fragment Ion Spectra-Mass Spectrometry (SWATH-MS).
HostingRepository	PRIDE
AnnounceDate	2025-08-06
AnnouncementXML	Submission_2025-08-06_15:27:14.323.xml
DigitalObjectIdentifier
ReviewLevel	Peer-reviewed dataset
DatasetOrigin	Original dataset
RepositorySupport	Unsupported dataset by repository
PrimarySubmitter	Torsten Kleffmann
SpeciesList	scientific name: Homo sapiens (Human); NCBI TaxID: 9606;
ModificationList	iodoacetamide derivatized residue
Instrument	TripleTOF 5600

Revision	Datetime	Status	ChangeLog Entry
0	2023-09-20 01:09:54	ID requested
⏵ 1	2025-08-06 15:27:15	announced

10.1038/s41598-023-49402-9;

Peppercorn K, Edgar CD, Kleffmann T, Tate WP, A pilot study on the immune cell proteome of long COVID patients shows changes to physiological pathways similar to those in myalgic encephalomyelitis/chronic fatigue syndrome. Sci Rep, 13(1):22068(2023) [pubmed]

submitter keyword: ME/CFS, SWATH-MS,Long COVID

Warren P. Tate
contact affiliation	Division of Health Sciences, Department of Biochemistry, School of Biomedical Sciences, University of Otago, Dunedin 9016, New Zealand
contact email	warren.tate@otago.ac.nz
lab head
Torsten Kleffmann
contact affiliation	Department of Biochemistry, University of Otago
contact email	torsten.kleffmann@otago.ac.nz
dataset submitter

Dataset FTP location NOTE: Most web browsers have now discontinued native support for FTP access within the browser window. But you can usually install another FTP app (we recommend FileZilla) and configure your browser to launch the external application when you click on this FTP link. Or otherwise, launch an app that supports FTP (like FileZilla) and use this address: ftp://ftp.pride.ebi.ac.uk/pride/data/archive/2025/08/PXD045508

PRIDE project URI

• PRIDE
  1. PXD045508
     1. Label: PRIDE project
     2. Name: Immune cell proteomes of Long COVID patients have functional changes similar to those in Myalgic Encephalomyelitis/Chronic Fatigue Syndrome.