PXD045507-2

PXD045507 is an original dataset announced via ProteomeXchange.

Title	Bacterial Protoplast-Derived Nanovesicles Carrying CRISPR Cas9 Tools Efficiently Re-educate Tumor-Associated Macrophages for Cancer Immunotherapy
Description	we developed an in vivo CRISPR-Cas9 genome editing system that targets tumor-associated macrophages (TAMs) via bacterial protoplast-derived nanovesicles (NVs) decorated with a pH-responsive PEG conjugated polymer and galactosamine-conjugated ligand
HostingRepository	iProX
AnnounceDate	2023-09-20
AnnouncementXML	Submission_2024-02-27_18:31:30.249.xml
DigitalObjectIdentifier
ReviewLevel	Peer-reviewed dataset
DatasetOrigin	Original dataset
RepositorySupport	Unsupported dataset by repository
PrimarySubmitter	Pingwen Shao
SpeciesList	scientific name: Escherichia coli BL21(DE3); NCBI TaxID: 469008;
ModificationList	No PTMs are included in the dataset
Instrument	TripleTOF 5600+

Revision	Datetime	Status	ChangeLog Entry
0	2023-09-20 00:49:41	ID requested
1	2023-09-20 00:49:57	announced
⏵ 2	2024-02-27 18:31:31	announced	2024-02-28: Update information.

Zhao M, Cheng X, Shao P, Dong Y, Wu Y, Xiao L, Cui Z, Sun X, Gao C, Chen J, Huang Z, Zhang J, Bacterial protoplast-derived nanovesicles carrying CRISPR-Cas9 tools re-educate tumor-associated macrophages for enhanced cancer immunotherapy. Nat Commun, 15(1):950(2024) [pubmed]

submitter keyword: CRISPR-Cas9,Bacterial Protoplast-Derived Nanovesicles,TAM

Junfeng Zhang
contact affiliation	State Key Laboratory of Pharmaceutical Biotechnology, School of Life Sciences, Nanjing University
contact email	jfzhang@nju.edu.cn
lab head
Pingwen Shao
contact affiliation	State Key Laboratory of Pharmaceutical Biotechnology, School of Life Sciences, Nanjing University
contact email	guanganxuanlv@gmail.com
dataset submitter

iProX dataset URI