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PXD045105-2

PXD045105 is an original dataset announced via ProteomeXchange.

Dataset Summary
TitleTGM1 interaction partners identification reveals possible TGM1 posttranslational modifiers
DescriptionTGM1 is an enzyme that cross-links structural proteins in the uppermost granular layer of the epidermis to form cornified envelopes. Cornified envelopes ensure functional stratum corneum and epidermal barrier formation. It has been suggested that the activity of TGM1 is regulated on a posttranslational level. To identify endogenous TGM1 interactors, Virotrap has been performed.
HostingRepositoryPRIDE
AnnounceDate2024-10-22
AnnouncementXMLSubmission_2024-10-22_06:27:45.480.xml
DigitalObjectIdentifierhttps://dx.doi.org/10.6019/PXD045105
ReviewLevelPeer-reviewed dataset
DatasetOriginOriginal dataset
RepositorySupportSupported dataset by repository
PrimarySubmitterMarta Surbek
SpeciesList scientific name: Homo sapiens (Human); NCBI TaxID: 9606;
ModificationListNo PTMs are included in the dataset
InstrumentQ Exactive HF
Dataset History
RevisionDatetimeStatusChangeLog Entry
02023-09-05 01:54:29ID requested
12024-01-26 12:56:15announced
22024-10-22 06:27:46announced2024-10-22: Updated project metadata.
Publication List
10.1038/s41598-023-48856-1;
10.6019/PXD045105;
Surbek M, Van de Steene T, Sachslehner AP, Golabi B, Griss J, Eyckerman S, Gevaert K, Eckhart L, Cornification of keratinocytes is associated with differential changes in the catalytic activity and the immunoreactivity of transglutaminase-1. Sci Rep, 13(1):21550(2023) [pubmed]
Keyword List
submitter keyword: cell model, Virotrap, skin, transglutamination, interaction partners,human, TGM1
Contact List
dr. Leopold
contact affiliationDepartment of Dermatology, Medical Unversity of Vienna
contact emailleopold.eckhart@meduniwien.ac.at
lab head
Marta Surbek
contact affiliationDepartment of Dermatology, Medical University of Vienna
contact emailmarta.surbek@meduniwien.ac.at
dataset submitter
Full Dataset Link List
Dataset FTP location
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PRIDE project URI
Repository Record List
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