PXD045083 is an
original dataset announced via ProteomeXchange.
Dataset Summary
| Title | Integrated proteogenomic analysis of outer membrane vesicles from hypervirulent Klebsiella pneumoniae |
| Description | Hypervirulent Klebsiella pneumoniae (hvKp) causes invasive infections and severe systemic inflammation. In this study, outer membrane vesicles (OMVs) derived from clinically isolated hvKp and classical K. pneumoniae (cKp) strains were characterized using an integrated proteogenomic workflow combining whole-genome sequencing and label-free LC–MS/MS proteomics. The dataset includes quantitative proteomic profiles of OMVs and whole-cell lysates together with strain-specific protein annotations for comparative analyses of OMVs cargo composition, functional annotation, and pathogenicity. |
| HostingRepository | PRIDE |
| AnnounceDate | 2026-07-22 |
| AnnouncementXML | Submission_2026-07-22_06:19:44.697.xml |
| DigitalObjectIdentifier | |
| ReviewLevel | Peer-reviewed dataset |
| DatasetOrigin | Original dataset |
| RepositorySupport | Unsupported dataset by repository |
| PrimarySubmitter | Jing Chen |
| SpeciesList | scientific name: Klebsiella pneumoniae; NCBI TaxID: NEWT:573; scientific name: Bacteria; NCBI TaxID: NCBITaxon:2; |
| ModificationList | iodoacetamide derivatized residue |
| Instrument | Q Exactive |
Dataset History
| Revision | Datetime | Status | ChangeLog Entry |
| 0 | 2023-09-04 07:19:52 | ID requested | |
| ⏵ 1 | 2026-07-22 06:19:45 | announced | |
Publication List
| Dataset with its publication pending |
Keyword List
| submitter keyword: Outer membrane vesicles,Klebsiella pneumoniae |
Contact List
| Jing Chen |
| contact affiliation | Department of Critical Care Medicine, Nanjing Zhongda Hospital, School of Medicine, Southeast University, Nanjing, 210009, People's Republic of China. |
| contact email | dongqingfei@126.com |
| lab head | |
| Jing Chen |
| contact affiliation | Department of Critical Care Medicine, Zhongda Hospital, School of Medicine, Southeast University |
| contact email | dongqingfei@126.com |
| dataset submitter | |
Full Dataset Link List
Dataset FTP location
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| PRIDE project URI |
Repository Record List
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[ - ]
- PRIDE
- PXD045083
- Label: PRIDE project
- Name: Integrated proteogenomic analysis of outer membrane vesicles from hypervirulent Klebsiella pneumoniae