PXD045070-1
PXD045070 is an original dataset announced via ProteomeXchange.
Dataset Summary
Title | Profiling of proteome changes in plasma of HIV-infected patients receiving antiretroviral therapy |
Description | Antiretroviral therapy (ART) prevents HIV-1 onward transmission and disease progression, leading to excellent prognosis people living with HIV-1 (PWH). However, significant side effects, complications and impaired immune reconstitution still persist along with ART. We aimed to profile proteome changes in plasma before and after ART to identify the molecular pathways altered by ART and finding potential targets to improve the health of PWH. |
HostingRepository | iProX |
AnnounceDate | 2022-03-08 |
AnnouncementXML | Submission_2023-12-24_21:03:56.695.xml |
DigitalObjectIdentifier | |
ReviewLevel | Peer-reviewed dataset |
DatasetOrigin | Original dataset |
RepositorySupport | Unsupported dataset by repository |
PrimarySubmitter | Ting Li |
SpeciesList | scientific name: Homo sapiens; NCBI TaxID: 9606; |
ModificationList | TMT6plex reporter+balance reagent acylated residue; iodoacetamide derivatized residue |
Instrument | Orbitrap Fusion Lumos |
Dataset History
Revision | Datetime | Status | ChangeLog Entry |
---|---|---|---|
0 | 2023-09-04 00:38:57 | ID requested | |
⏵ 1 | 2023-12-24 21:03:57 | announced |
Publication List
Li T, Qu H, Ding H, Deng H, Chen Y, Profiling of proteome changes in plasma of HIV-infected patients receiving antiretroviral therapy. Proteomics Clin Appl, 16(6):e2100099(2022) [pubmed] |
Keyword List
submitter keyword: ART, HIV-1, proteomics |
Contact List
Haiteng Deng | |
---|---|
contact affiliation | Tsinghua University |
contact email | dht@mail.tsinghua.edu.cn |
lab head | |
Ting Li | |
contact affiliation | Tsinghua University |
contact email | t-li18@mails.tsinghua.edu.cn |
dataset submitter |
Full Dataset Link List
iProX dataset URI |