PXD044946-1
PXD044946 is an original dataset announced via ProteomeXchange.
Dataset Summary
| Title | The target landscape of clinical covalent drugs |
| Description | we identified the targets of clinical covalent drugs using an optimized analytical platform-QTRP (Quantitative Thiol Reactivity Profiling), and aim to identify new targets for illuminating uncharacterized covalent mechanisms of action and for the repurposing of an existing drug as a covalent recruiter for targeted protein degradation |
| HostingRepository | iProX |
| AnnounceDate | 2023-08-30 |
| AnnouncementXML | Submission_2023-08-29_20:50:00.744.xml |
| DigitalObjectIdentifier | |
| ReviewLevel | Peer-reviewed dataset |
| DatasetOrigin | Original dataset |
| RepositorySupport | Unsupported dataset by repository |
| PrimarySubmitter | Caiping Tian |
| SpeciesList | scientific name: Homo sapiens; NCBI TaxID: 9606; |
| ModificationList | iodoacetamide derivatized residue; dimethylated residue |
| Instrument | Q Exactive HF-X; Q Exactive Plus |
Dataset History
| Revision | Datetime | Status | ChangeLog Entry |
|---|---|---|---|
| 0 | 2023-08-29 20:49:36 | ID requested | |
| ⏵ 1 | 2023-08-29 20:50:01 | announced |
Publication List
| Dataset with its publication pending |
Keyword List
| submitter keyword: covalent drugs, protein-protein interaction, targeted protein degradation |
Contact List
| Jing Yang | |
|---|---|
| contact affiliation | National Center for Protein Sciences Beijing |
| contact email | yangjing@ncpsb.org.cn |
| lab head | |
| Caiping Tian | |
| contact affiliation | Tsinghua UnivUersity; National Center for Protein Sciences Beijing |
| contact email | tiancaiping2000@126.com |
| dataset submitter | |
Full Dataset Link List
| iProX dataset URI |
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