PXD044927-1

PXD044927 is an original dataset announced via ProteomeXchange.

Dataset Summary

Title	Shotgun proteomics of mitochondria from hearts of rats submitted to ischemia-reperfusion in normoglycemia and hyperglycemia conditions
Description	Proteomic analysis of cardiac mitochondria iolated from hearts of rats perfused in normoglycemic or hyperglycemic Krebs-Henseleit buffer buffer and submitted to ex-vivo IR. Comparisons were performed to reveal the impact of HG on heart sensitivity to IR.
HostingRepository	PRIDE
AnnounceDate	2024-05-02
AnnouncementXML	Submission_2024-05-02_08:48:36.121.xml
DigitalObjectIdentifier	https://dx.doi.org/10.6019/PXD044927
ReviewLevel	Peer-reviewed dataset
DatasetOrigin	Original dataset
RepositorySupport	Supported dataset by repository
PrimarySubmitter	Jean ARMENGAUD
SpeciesList	scientific name: Rattus norvegicus (Rat); NCBI TaxID: 10116;
ModificationList	methionine oxidation with neutral loss of 64 Da; N-ethylmaleimide derivatized cysteine; acetylated residue; deamidated L-asparagine; deamidated L-glutamine; iodoacetamide derivatized residue
Instrument	Q Exactive HF

Dataset History

Revision	Datetime	Status	ChangeLog Entry
0	2023-08-29 03:21:05	ID requested
⏵ 1	2024-05-02 08:48:37	announced

Publication List

10.1016/j.redox.2024.103044;
Dubois M, Boulghobra D, Rochebloine G, Pallot F, Yehya M, Bornard I, Gayrard S, Coste F, Walther G, Meyer G, Gaillard JC, Armengaud J, Alpha-Bazin B, Reboul C, Hyperglycemia triggers RyR2-dependent alterations of mitochondrial calcium homeostasis in response to cardiac ischemia-reperfusion: Key role of DRP1 activation. Redox Biol, 70():103044(2024) [pubmed]
10.6019/PXD044927;

10.1016/j.redox.2024.103044;

Dubois M, Boulghobra D, Rochebloine G, Pallot F, Yehya M, Bornard I, Gayrard S, Coste F, Walther G, Meyer G, Gaillard JC, Armengaud J, Alpha-Bazin B, Reboul C, Hyperglycemia triggers RyR2-dependent alterations of mitochondrial calcium homeostasis in response to cardiac ischemia-reperfusion: Key role of DRP1 activation. Redox Biol, 70():103044(2024) [pubmed]

10.6019/PXD044927;

Keyword List

submitter keyword: hyperglycemia, ischemia-reperfusion,Shotgun proteomics, rattus norvegicus

submitter keyword: hyperglycemia, ischemia-reperfusion,Shotgun proteomics, rattus norvegicus

Contact List

ARMENGAUD Jean
contact affiliation	CEA-Marcoule, ProGénoMIX platform, DRF-Li2D, 30207 Bagnols-sur-Cèze, France
contact email	jean.armengaud@cea.fr
lab head
Jean ARMENGAUD
contact affiliation	Li2D
contact email	jean.armengaud@cea.fr
dataset submitter

Full Dataset Link List

Dataset FTP location NOTE: Most web browsers have now discontinued native support for FTP access within the browser window. But you can usually install another FTP app (we recommend FileZilla) and configure your browser to launch the external application when you click on this FTP link. Or otherwise, launch an app that supports FTP (like FileZilla) and use this address: ftp://ftp.pride.ebi.ac.uk/pride/data/archive/2024/05/PXD044927
PRIDE project URI

Dataset FTP location
NOTE: Most web browsers have now discontinued native support for FTP access within the browser window. But you can usually install another FTP app (we recommend FileZilla) and configure your browser to launch the external application when you click on this FTP link. Or otherwise, launch an app that supports FTP (like FileZilla) and use this address: ftp://ftp.pride.ebi.ac.uk/pride/data/archive/2024/05/PXD044927

PRIDE project URI

Repository Record List

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