PXD044897-2
PXD044897 is an original dataset announced via ProteomeXchange.
Dataset Summary
| Title | R406 binding site on TAK1 identified by MS |
| Description | We identified of R406 and its pro-drug R788 for the treatment of cancer by inducing necroptosis. |
| HostingRepository | iProX |
| AnnounceDate | 2023-08-28 |
| AnnouncementXML | Submission_2024-03-27_20:45:35.585.xml |
| DigitalObjectIdentifier | |
| ReviewLevel | Peer-reviewed dataset |
| DatasetOrigin | Original dataset |
| RepositorySupport | Unsupported dataset by repository |
| PrimarySubmitter | Bing Shan |
| SpeciesList | scientific name: Homo sapiens; NCBI TaxID: 9606; |
| ModificationList | No PTMs are included in the dataset |
| Instrument | Q Exactive |
Dataset History
| Revision | Datetime | Status | ChangeLog Entry |
|---|---|---|---|
| 0 | 2023-08-27 20:42:11 | ID requested | |
| 1 | 2023-08-27 20:42:32 | announced | |
| ⏵ 2 | 2024-03-27 20:45:36 | announced | 2024-03-28: Update information. |
Publication List
| Sun W, Wu G, Tian X, Qi C, Liu J, Tong Y, Zhang M, Gao J, Cao Z, Zhang Y, Liu Z, Tian X, Wu P, Peng C, Li J, Tan L, Shan B, Liu J, Li Y, Yuan J, Small molecule activators of TAK1 promotes its activity-dependent ubiquitination and TRAIL-mediated tumor cell death. Proc Natl Acad Sci U S A, 120(39):e2308079120(2023) [pubmed] |
Keyword List
| submitter keyword: R406, TAK1 |
Contact List
| Junying Yuan | |
|---|---|
| contact affiliation | Shanghai Insititute of Organic Chemistry, Chinese Academy of Sciences |
| contact email | junying_yuan@sioc.ac.cn |
| lab head | |
| Bing Shan | |
| contact affiliation | Shanghai Insititute of Organic Chemistry, Chinese Academy of Sciences |
| contact email | shanbing@sioc.ac.cn |
| dataset submitter | |
Full Dataset Link List
| iProX dataset URI |
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