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PXD044845-1

PXD044845 is an original dataset announced via ProteomeXchange.

Dataset Summary
TitleEye proteome of Drosophila melanogaster
DescriptionWe report the proteome composition of the Drosophila eye – a compound organ that is highly enriched in membrane proteins. The fly eye is a popular model to study the physiology of vision by means of genetic, pharmacological, and dietary interference.While the eye transcriptome and development-related changes of gene expression profiles have been extensively studied, little is known about the eye proteome.we employed GeLC-MS/MS to identify and rank the abundances of 3516 eye proteins. Moreover, we applied our MS Western method to determine the absolute (molar) abundances of a related set of proteins that are important for photoreceptor structure (including maintenance) and function (phototransduction). Altogether, we provide a comprehensive and expandable proteomics resource that will be valuable for a variety of studies of ocular biochemistry, physiology, and development.
HostingRepositoryPRIDE
AnnounceDate2024-08-09
AnnouncementXMLSubmission_2024-08-09_03:20:45.358.xml
DigitalObjectIdentifier
ReviewLevelPeer-reviewed dataset
DatasetOriginOriginal dataset
RepositorySupportUnsupported dataset by repository
PrimarySubmitterMukesh Kumar
SpeciesList scientific name: Drosophila melanogaster (Fruit fly); NCBI TaxID: 7227;
ModificationListmonohydroxylated residue; iodoacetamide derivatized residue
InstrumentQ Exactive HF; LTQ Orbitrap Velos
Dataset History
RevisionDatetimeStatusChangeLog Entry
02023-08-25 00:54:54ID requested
12024-08-09 03:20:46announced
Publication List
10.1002/pmic.202300330;
Keyword List
submitter keyword: Eye, GeLC-MS/MS, Proteomics, Drosophila melanogaster
Contact List
Andrej Shevchenko
contact affiliationMax Planck Institute of Molecular Cell Biology and Genetics, Dresden, Germany
contact emailshevchenko@mpi-cbg.de
lab head
Mukesh Kumar
contact affiliationCell Signaling Technology
contact emailmukeshbiot@gmail.com
dataset submitter
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Dataset FTP location
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