PXD044682-1

PXD044682 is an original dataset announced via ProteomeXchange.

Dataset Summary

Title	Phosphoproteomic Landscape of Pseudorabies Virus Infection Reveals Multiple Potential Antiviral Targets
Description	A quantitative phosphoproteome was conducted to explore the phosphorylation changes and host cellular responses upon PRV infection. Besides, the characteristics of the phosphorylated proteins were analyzed, including molecular distribution, percentage of the phosphorylated (STY) sites, and phosphorylated motifs. Additionally, the GO and KEGG analyses of the significantly changed phophoproteins were performed. Finally, DNMT1, HDAC6, EGFR, GRK2, VIM, and G3BP1 were chosen for analysis of their effect on PRV replication using an inhibitory-based experiment, and the results showed that all these proteins are necessary for efficient PRV replication.
HostingRepository	PRIDE
AnnounceDate	2023-11-17
AnnouncementXML	Submission_2023-11-16_17:33:27.733.xml
DigitalObjectIdentifier
ReviewLevel	Peer-reviewed dataset
DatasetOrigin	Original dataset
RepositorySupport	Unsupported dataset by repository
PrimarySubmitter	Zongyi Bo
SpeciesList	scientific name: Sus scrofa domesticus (domestic pig); NCBI TaxID: 9825;
ModificationList	phosphorylated residue
Instrument	Q Exactive HF

Dataset History

Revision	Datetime	Status	ChangeLog Entry
0	2023-08-21 01:37:48	ID requested
⏵ 1	2023-11-16 17:33:28	announced

Publication List

Dataset with its publication pending

Dataset with its publication pending

Keyword List

submitter keyword: phosphoproteomic landscape,Pseudorabies Virus, antiviral targets, virus-host interaction

submitter keyword: phosphoproteomic landscape,Pseudorabies Virus, antiviral targets, virus-host interaction

Contact List

Zongyi Bo
contact affiliation	Yangzhou university
contact email	zybo@yzu.edu.cn
lab head
Zongyi Bo
contact affiliation	Yangzhou agriculture university
contact email	zybo@yzu.edu.cn
dataset submitter

Full Dataset Link List

Dataset FTP location NOTE: Most web browsers have now discontinued native support for FTP access within the browser window. But you can usually install another FTP app (we recommend FileZilla) and configure your browser to launch the external application when you click on this FTP link. Or otherwise, launch an app that supports FTP (like FileZilla) and use this address: ftp://ftp.pride.ebi.ac.uk/pride/data/archive/2023/11/PXD044682
PRIDE project URI

Dataset FTP location
NOTE: Most web browsers have now discontinued native support for FTP access within the browser window. But you can usually install another FTP app (we recommend FileZilla) and configure your browser to launch the external application when you click on this FTP link. Or otherwise, launch an app that supports FTP (like FileZilla) and use this address: ftp://ftp.pride.ebi.ac.uk/pride/data/archive/2023/11/PXD044682

PRIDE project URI

Repository Record List

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