PXD044611-1
PXD044611 is an original dataset announced via ProteomeXchange.
Dataset Summary
| Title | SUMOylation fine tunes the transcriptional activity of endothelial HEY1 in the regulation of angiogenesis |
| Description | Reversible HEY1 SUMOylation is a molecular mechanism that coordinates endothelial angiogenic signaling and angiogenesis, both in physiological and pathological milieus, by fine tuning the transcriptional activity of HEY1. Specifically, S UMOylation facilitates the formation of the HEY1 transcriptional complex and enhances its DNA binding capability in endothelial cells. |
| HostingRepository | iProX |
| AnnounceDate | 2023-08-18 |
| AnnouncementXML | Submission_2023-10-07_00:32:15.891.xml |
| DigitalObjectIdentifier | |
| ReviewLevel | Peer-reviewed dataset |
| DatasetOrigin | Original dataset |
| RepositorySupport | Unsupported dataset by repository |
| PrimarySubmitter | Ruizhe Ren |
| SpeciesList | scientific name: Homo sapiens; NCBI TaxID: 9606; |
| ModificationList | No PTMs are included in the dataset |
| Instrument | Q Exactive HF |
Dataset History
| Revision | Datetime | Status | ChangeLog Entry |
|---|---|---|---|
| 0 | 2023-08-17 21:00:32 | ID requested | |
| ⏵ 1 | 2023-10-07 00:32:16 | announced | |
| 2 | 2024-05-22 19:59:54 | announced | 2024-05-23: Update information. |
Publication List
| Dataset with its publication pending |
Keyword List
| submitter keyword: SUMOylation, HEY1 , angiogenesis , transcription |
Contact List
| Luyang Yu | |
|---|---|
| contact affiliation | Zhejiang University |
| contact email | luyangyu@zju.edu.cn |
| lab head | |
| Ruizhe Ren | |
| contact affiliation | Zhejiang University |
| contact email | renrzmiracle@zju.edu.cn |
| dataset submitter | |
Full Dataset Link List
| iProX dataset URI |
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