PXD044474-1

PXD044474 is an original dataset announced via ProteomeXchange.

Title	Metabolomics insights for acquired platinum chemoresistance of A549 cells induced by chronic arsenic exposure
Description	Arsenic exposure is considered as a risk factor for lung cancer. However, toxic effects of the metabolic mechanism responsible for arsenic-induced toxicity and especially chronic effects, are less known. Here we constructed a cell model of lung adenocarcinoma A549 cells by chronic arsenic exposure. Cell-based experiments showed that A549 cells display platinum resistance with chronic exposure of arsenic. The metabolic response of A549 cells to arsenic exposure was profiled by gas chromatography-mass spectrometry.
HostingRepository	iProX
AnnounceDate	2023-08-09
AnnouncementXML	Submission_2024-07-31_19:43:18.243.xml
DigitalObjectIdentifier
ReviewLevel	Peer-reviewed dataset
DatasetOrigin	Original dataset
RepositorySupport	Unsupported dataset by repository
PrimarySubmitter	Yang Zhou
SpeciesList	scientific name: Homo sapiens; NCBI TaxID: 9606;
ModificationList	No PTMs are included in the dataset
Instrument	quadrupole

Revision	Datetime	Status	ChangeLog Entry
0	2023-08-09 20:40:31	ID requested
⏵ 1	2024-07-31 19:43:18	announced

Dataset with its publication pending

submitter keyword: Arsenic, A549 cells, metabolomics, chemotherapeutic resistance, GC-MS

Yang Zhou
contact affiliation	The Affiliated Li Huili Hospital, Ningbo University
contact email	zhouyang610@163.com
lab head
Yang Zhou
contact affiliation	The Affiliated Li Huili Hospital, Ningbo University
contact email	zhouyang610@163.com
dataset submitter

iProX dataset URI