PXD044474-1
PXD044474 is an original dataset announced via ProteomeXchange.
Dataset Summary
Title | Metabolomics insights for acquired platinum chemoresistance of A549 cells induced by chronic arsenic exposure |
Description | Arsenic exposure is considered as a risk factor for lung cancer. However, toxic effects of the metabolic mechanism responsible for arsenic-induced toxicity and especially chronic effects, are less known. Here we constructed a cell model of lung adenocarcinoma A549 cells by chronic arsenic exposure. Cell-based experiments showed that A549 cells display platinum resistance with chronic exposure of arsenic. The metabolic response of A549 cells to arsenic exposure was profiled by gas chromatography-mass spectrometry. |
HostingRepository | iProX |
AnnounceDate | 2023-08-09 |
AnnouncementXML | Submission_2024-07-31_19:43:18.243.xml |
DigitalObjectIdentifier | |
ReviewLevel | Peer-reviewed dataset |
DatasetOrigin | Original dataset |
RepositorySupport | Unsupported dataset by repository |
PrimarySubmitter | Yang Zhou |
SpeciesList | scientific name: Homo sapiens; NCBI TaxID: 9606; |
ModificationList | No PTMs are included in the dataset |
Instrument | quadrupole |
Dataset History
Revision | Datetime | Status | ChangeLog Entry |
---|---|---|---|
0 | 2023-08-09 20:40:31 | ID requested | |
⏵ 1 | 2024-07-31 19:43:18 | announced |
Publication List
Dataset with its publication pending |
Keyword List
submitter keyword: Arsenic, A549 cells, metabolomics, chemotherapeutic resistance, GC-MS |
Contact List
Yang Zhou | |
---|---|
contact affiliation | The Affiliated Li Huili Hospital, Ningbo University |
contact email | zhouyang610@163.com |
lab head | |
Yang Zhou | |
contact affiliation | The Affiliated Li Huili Hospital, Ningbo University |
contact email | zhouyang610@163.com |
dataset submitter |
Full Dataset Link List
iProX dataset URI |