PXD044427-1

PXD044427 is an original dataset announced via ProteomeXchange.

Dataset Summary

Title	The protein interactomes of Acute Myeloid Leukemia-associated oncogenic fusion proteins predict potential mechanisms of action
Description	TurboID (biotin proximity ligase) was fused to AML-associated oncofusions (PML::RARA, RUNX1::RUNX1T1, CBFB::MYH11), wildtype NPM1, or mutated NPMc and expressed in murine hematopoietic stem/progenitor cells using MSCV-based retroviruses to identify key interacting proteins in primary hematopoietic cells.
HostingRepository	MassIVE
AnnounceDate	2023-12-14
AnnouncementXML	Submission_2023-12-14_09:13:03.703.xml
DigitalObjectIdentifier
ReviewLevel	Non peer-reviewed dataset
DatasetOrigin	Original dataset
RepositorySupport	Supported dataset by repository
PrimarySubmitter	Jim Malone
SpeciesList	scientific name: Mus musculus; common name: house mouse; NCBI TaxID: 10090;
ModificationList	Carbamidomethyl; Deamidated; Glu->pyro-Glu; Xlink:DTSSP[88]; Oxidation
Instrument	timsTOF Pro

Dataset History

Revision	Datetime	Status	ChangeLog Entry
0	2023-08-07 20:48:00	ID requested
⏵ 1	2023-12-14 09:13:04	announced

Publication List

no publication

no publication

Keyword List

submitter keyword: TurboID, proximity labeling, AML1::ETO, AML1-ETO, CBFB::MYH11, CBFB-MYH11, RUNX1::RUNX1T1, RUNX1-RUNX1T1, PML::RARA, PML-RARA, NPM1, NPMc, nucleophosmin, CBFB, RUNX, RUNX1, MYH11

submitter keyword: TurboID, proximity labeling, AML1::ETO, AML1-ETO, CBFB::MYH11, CBFB-MYH11, RUNX1::RUNX1T1, RUNX1-RUNX1T1, PML::RARA, PML-RARA, NPM1, NPMc, nucleophosmin, CBFB, RUNX, RUNX1, MYH11

Contact List

Timothy J. Ley
contact affiliation	Washington University in St. Louis
contact email	timley@wustl.edu
lab head
Jim Malone
contact affiliation	Washington University Sch
contact email	jmalone@wustl.edu
dataset submitter

Full Dataset Link List

MassIVE dataset URI
Dataset FTP location NOTE: Most web browsers have now discontinued native support for FTP access within the browser window. But you can usually install another FTP app (we recommend FileZilla) and configure your browser to launch the external application when you click on this FTP link. Or otherwise, launch an app that supports FTP (like FileZilla) and use this address: ftp://massive.ucsd.edu/MSV000092615/

MassIVE dataset URI

Dataset FTP location
NOTE: Most web browsers have now discontinued native support for FTP access within the browser window. But you can usually install another FTP app (we recommend FileZilla) and configure your browser to launch the external application when you click on this FTP link. Or otherwise, launch an app that supports FTP (like FileZilla) and use this address: ftp://massive.ucsd.edu/MSV000092615/