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PXD044328-1

PXD044328 is an original dataset announced via ProteomeXchange.

Dataset Summary
TitleStructural basis of the human transcriptional Mediator complex modulated by its dissociable Kinase module
DescriptionThe Mediator complex consists of a Core and a dissociable Kinase module. This project is to understand the binding mode between the Core and Kinase module. Both Mediator complex and its Kinase module were individually crosslinked and analyzed by XL-MS.
HostingRepositoryPRIDE
AnnounceDate2024-11-21
AnnouncementXMLSubmission_2024-11-20_21:00:05.586.xml
DigitalObjectIdentifier
ReviewLevelPeer-reviewed dataset
DatasetOriginOriginal dataset
RepositorySupportUnsupported dataset by repository
PrimarySubmitterHee Jong Kim
SpeciesList scientific name: Homo sapiens (Human); NCBI TaxID: 9606;
ModificationListNo PTMs are included in the dataset
InstrumentQ Exactive HF
Dataset History
RevisionDatetimeStatusChangeLog Entry
02023-08-03 09:43:27ID requested
12024-11-20 21:00:06announced
Publication List
Chao TC, Chen SF, Kim HJ, Tang HC, Tseng HC, Xu A, Palao L, Khadka S, Li T, Huang MF, Lee DF, Murakami K, Boyer TG, Tsai KL, Structural basis of the human transcriptional Mediator regulated by its dissociable kinase module. Mol Cell, 84(20):3932-3949.e10(2024) [pubmed]
10.1016/j.molcel.2024.09.001;
Keyword List
submitter keyword: Human, transcription, Mediator, CDK8
Contact List
Kenji Murakami
contact affiliationUniversity of Pennsylvania, School of Medicine
contact emailkenjim@pennmedicine.upenn.edu
lab head
Hee Jong Kim
contact affiliationUniversity of Pennsylvania
contact emailheejong@heejong.com
dataset submitter
Full Dataset Link List
Dataset FTP location
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PRIDE project URI
Repository Record List
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