PXD044308-1
PXD044308 is an original dataset announced via ProteomeXchange.
Dataset Summary
Title | Human astrocyte secretome data |
Description | In late-onset sporadic Alzheimer’s disease (AD), the most prevalent and strongest risk factor is the ε4 allele of the apolipoprotein E (APOE4). To investigate the pathophysiological effects of the APOE4 genotype in the human cellular context, we generated isogenic iPSC-derived astrocytes bearing APOE4 alleles from APOE3 control iPSC. Next, to identify astrocytic APOE4-specific secreted proteomes, we performed a mass spectrometry using culture media from human astrocytes carrying APOE3 or APOE4. |
HostingRepository | jPOST |
AnnounceDate | 2023-09-01 |
AnnouncementXML | Submission_2023-08-31_21:54:49.018.xml |
DigitalObjectIdentifier | |
ReviewLevel | Non peer-reviewed dataset |
DatasetOrigin | Original dataset |
RepositorySupport | Unsupported dataset by repository |
PrimarySubmitter | Hirotaka Watanabe |
SpeciesList | scientific name: Homo sapiens (Human); NCBI TaxID: 9606; |
ModificationList | S-carboxamidomethyl-L-cysteine; Acetyl; L-methionine sulfoxide |
Instrument | Orbitrap Fusion Lumos |
Dataset History
Revision | Datetime | Status | ChangeLog Entry |
---|---|---|---|
0 | 2023-08-02 19:37:04 | ID requested | |
⏵ 1 | 2023-08-31 21:54:49 | announced |
Publication List
Dataset with its publication pending |
Keyword List
submitter keyword: Human, Astrocyte |
Contact List
Hideyuki Okano | |
---|---|
lab head | |
Hirotaka Watanabe | |
contact affiliation | Keio University |
dataset submitter |
Full Dataset Link List
jPOST dataset URI |
Dataset FTP location NOTE: Most web browsers have now discontinued native support for FTP access within the browser window. But you can usually install another FTP app (we recommend FileZilla) and configure your browser to launch the external application when you click on this FTP link. Or otherwise, launch an app that supports FTP (like FileZilla) and use this address: ftp://ftp.jpostdb.org/JPST002270/ |