PXD044287-1

PXD044287 is an original dataset announced via ProteomeXchange.

Title	Targeting IRE1α reprograms the tumor microenvironment and enhances anti-tumor immunity in prostate cancer
Description	Unfolded protein response (UPR) is a central stress response pathway in normal cells that is hijacked by tumor cells for their survival. However, how activation of UPR in cancer cells shapes the tumor microenvironment (TME) remain largely unexplored. Here, we investigated the role of IRE1α-XBP1s on modulation of TME dynamics in prostate cancer (PCa).
HostingRepository	PRIDE
AnnounceDate	2024-08-28
AnnouncementXML	Submission_2024-08-28_08:11:21.876.xml
DigitalObjectIdentifier
ReviewLevel	Peer-reviewed dataset
DatasetOrigin	Original dataset
RepositorySupport	Unsupported dataset by repository
PrimarySubmitter	Frank Stein
SpeciesList	scientific name: Mus musculus (Mouse); NCBI TaxID: 10090;
ModificationList	No PTMs are included in the dataset
Instrument	Orbitrap Fusion Lumos

Revision	Datetime	Status	ChangeLog Entry
0	2023-08-02 01:09:21	ID requested
⏵ 1	2024-08-28 08:11:22	announced

Dataset with its publication pending

submitter keyword: IRE1 prostate cancer tumor microenvironment

Fahri Saatcioglu
contact affiliation	University of Oslo
contact email	fahri.saatcioglu@ibv.uio.no
lab head
Frank Stein
contact affiliation	EMBL
contact email	frank.stein@embl.de
dataset submitter

Dataset FTP location NOTE: Most web browsers have now discontinued native support for FTP access within the browser window. But you can usually install another FTP app (we recommend FileZilla) and configure your browser to launch the external application when you click on this FTP link. Or otherwise, launch an app that supports FTP (like FileZilla) and use this address: ftp://ftp.pride.ebi.ac.uk/pride/data/archive/2024/08/PXD044287

PRIDE project URI

• PRIDE
  1. PXD044287
     1. Label: PRIDE project
     2. Name: Targeting IRE1α reprograms the tumor microenvironment and enhances anti-tumor immunity in prostate cancer