PXD044245 is an
original dataset announced via ProteomeXchange.
Dataset Summary
| Title | PVRL2 suppresses anti-tumor immunity through PVRIG- and TIGIT-independent pathways |
| Description | Here, we share discovery proteomics data associated with a larger study to expose new immunoregulatory mechanisms in cancer. PVRL2 was identified in both tumor cells and exosomes, and the role of this surface protein in the immune response to cancer was explored in further studies. |
| HostingRepository | PRIDE |
| AnnounceDate | 2024-05-21 |
| AnnouncementXML | Submission_2024-05-21_12:04:25.730.xml |
| DigitalObjectIdentifier | |
| ReviewLevel | Peer-reviewed dataset |
| DatasetOrigin | Original dataset |
| RepositorySupport | Unsupported dataset by repository |
| PrimarySubmitter | James Byrnes |
| SpeciesList | scientific name: Homo sapiens (Human); NCBI TaxID: 9606; |
| ModificationList | 2-pyrrolidone-5-carboxylic acid (Glu); acetylated residue; iodoacetamide derivatized residue |
| Instrument | Q Exactive Plus |
Dataset History
| Revision | Datetime | Status | ChangeLog Entry |
|---|
| 0 | 2023-07-31 21:03:45 | ID requested | |
| ⏵ 1 | 2024-05-21 12:04:26 | announced | |
| 2 | 2024-10-22 06:40:38 | announced | 2024-10-22: Updated project metadata. |
Publication List
| Yang J, Wang L, Byrnes JR, Kirkemo LL, Driks H, Belair CD, Aguilar OA, Lanier LL, Wells JA, Fong L, Blelloch R, PVRL2 Suppresses Antitumor Immunity through PVRIG- and TIGIT-independent Pathways. Cancer Immunol Res, 12(5):575-591(2024) [pubmed] |
| 10.1158/2326-6066.cir-23-0722; |
Keyword List
| submitter keyword: immunology,cancer |
Contact List
| James Wells |
|---|
| contact affiliation | Pharmaceutical Chemistry and Molecular and Cellular Pharmacology Departments, University if California, San Francisco |
| contact email | jim.wells@ucsf.edu |
| lab head | |
| James Byrnes |
|---|
| contact affiliation | Unviersity of California, San Francisco |
| contact email | byrnes.jamesr@gmail.com |
| dataset submitter | |
Full Dataset Link List
Dataset FTP location
NOTE: Most web browsers have now discontinued native support for FTP access within the browser window. But you can usually install another FTP app (we recommend FileZilla) and configure your browser to launch the external application when you click on this FTP link. Or otherwise, launch an app that supports FTP (like FileZilla) and use this address: ftp://ftp.pride.ebi.ac.uk/pride/data/archive/2024/05/PXD044245 |
| PRIDE project URI |
Repository Record List
[ + ]
[ - ]
- PRIDE
- PXD044245
- Label: PRIDE project
- Name: PVRL2 suppresses anti-tumor immunity through PVRIG- and TIGIT-independent pathways
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