PXD044086 is an
original dataset announced via ProteomeXchange.
Dataset Summary
| Title | Human lung cancer TMT-labeling LC-MS |
| Description | Although the paradigm of cancer treatment has changed with the recent development of drugs targeting immune checkpoints (PD-1, PD-L1, etc.), there is still a need for new targets for anticancer drugs. To discover new potential targets for immunotherapy, we compared membrane protein expression in non-small cell lung cancer cells versus normal lung cancer cells and NSCLC cell lines with low and high PD-L1 expression using mass spectrometry. As a result, it was confirmed that membrane protein, which is one of the most highly expressed proteins in NSCLC cell lines, is highly expressed in normal cells and highly expressed in cells with low PD-L1 expression. |
| HostingRepository | PRIDE |
| AnnounceDate | 2024-01-08 |
| AnnouncementXML | Submission_2024-01-07_16:12:19.925.xml |
| DigitalObjectIdentifier | |
| ReviewLevel | Peer-reviewed dataset |
| DatasetOrigin | Original dataset |
| RepositorySupport | Unsupported dataset by repository |
| PrimarySubmitter | Jae-Sik Shin |
| SpeciesList | scientific name: Homo sapiens (Human); NCBI TaxID: 9606; |
| ModificationList | TMT6plex-126 reporter+balance reagent acylated residue |
| Instrument | LTQ Orbitrap |
Dataset History
| Revision | Datetime | Status | ChangeLog Entry |
|---|
| 0 | 2023-07-25 17:23:44 | ID requested | |
| ⏵ 1 | 2024-01-07 16:12:20 | announced | |
Publication List
| Dataset with its publication pending |
Keyword List
| ProteomeXchange project tag: Cancer (B/D-HPP), Biology/Disease-Driven Human Proteome Project (B/D-HPP), Human Proteome Project |
| submitter keyword: TMT-labeling LC-MS, immune checkpoint,Human lung cancer, membrane protein |
Contact List
| Jae-Sik Shin |
|---|
| contact affiliation | Wellmarker Bio, Republic of Korea |
| contact email | sleezee@wmbio.co |
| lab head | |
| Jae-Sik Shin |
|---|
| contact affiliation | Wellmarker Bio |
| contact email | sleezee@wmbio.co |
| dataset submitter | |
Full Dataset Link List
Dataset FTP location
NOTE: Most web browsers have now discontinued native support for FTP access within the browser window. But you can usually install another FTP app (we recommend FileZilla) and configure your browser to launch the external application when you click on this FTP link. Or otherwise, launch an app that supports FTP (like FileZilla) and use this address: ftp://ftp.pride.ebi.ac.uk/pride/data/archive/2024/01/PXD044086 |
| PRIDE project URI |
Repository Record List
[ + ]
[ - ]
- PRIDE
- PXD044086
- Label: PRIDE project
- Name: Human lung cancer TMT-labeling LC-MS
to receive all new ProteomeXchange dataset release announcements!
