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PXD044069-1

PXD044069 is an original dataset announced via ProteomeXchange.

Dataset Summary
TitleThe proteome of personalized tissue-engineered veins
DescriptionTissue-engineered veins were generated by reconditioning decellularized veins from both human and pig with whole-blood from respective species. Decellularized human vena femoralis from three donor were reconditioned with human whole blood from four donors. In addition, decellularized pig vena cava from three donors were reconditioned with pig whole blood from three different donors. The proteomes of the tissue-engineered veins were investigated applying the TMT-based proteomics to explore differences between species, regarding the gain of biological material by the reconditioning process.
HostingRepositoryPRIDE
AnnounceDate2024-05-21
AnnouncementXMLSubmission_2024-05-21_11:39:00.255.xml
DigitalObjectIdentifier
ReviewLevelPeer-reviewed dataset
DatasetOriginOriginal dataset
RepositorySupportUnsupported dataset by repository
PrimarySubmitterGeorgios Mermelekas
SpeciesList scientific name: Sus scrofa domesticus (domestic pig); NCBI TaxID: 9825; scientific name: Homo sapiens (Human); NCBI TaxID: 9606;
ModificationListmonohydroxylated residue; iodoacetamide derivatized residue
InstrumentQ Exactive HF
Dataset History
RevisionDatetimeStatusChangeLog Entry
02023-07-25 06:49:14ID requested
12024-05-21 11:39:01announced
Publication List
Larsson S, Holmgren S, Jenndahl L, Ulfenborg B, Strehl R, Synnergren J, Ghosheh N, Proteome of Personalized Tissue-Engineered Veins. ACS Omega, 9(13):14805-14817(2024) [pubmed]
10.1021/acsomega.3c07098;
Keyword List
submitter keyword: ECM, personalized medicine, ATMP,Tissue-engineering, vascular diseases
Contact List
Janne Lehtiƶ
contact affiliationDept. Oncology Pathology, Karolinska Institutet, and Scilifelab, Stockholm, Sweden
contact emailjanne.lehtio@ki.se
lab head
Georgios Mermelekas
contact affiliationKarolinska Institutet
contact emailgeorgios.mermelekas@scilifelab.se
dataset submitter
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Dataset FTP location
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