PXD044062 is an
original dataset announced via ProteomeXchange.
Dataset Summary
Title | Comparative analysis of the proteome of Th2 lymphocytes from WT or ASB2 KO mice |
Description | ASB2α is an E3 ubiquitin ligase which is upregulated during Th2 differentiation of naive CD4+ T lymphocyte, and which is known to trigger ubiquitylation and proteasomal degradation of filamins (FLN) a and b. Because E3 ubiquitin ligases often ubiquitylate several substrates, we used an unbiased and broad mass spectrometry approach to identify ASB2α substrates in Th2 lymphocytes generated from naïve CD4+ T lymphocytes of control or ASB2 KO mice. |
HostingRepository | PRIDE |
AnnounceDate | 2024-09-24 |
AnnouncementXML | Submission_2024-09-24_02:08:47.908.xml |
DigitalObjectIdentifier | |
ReviewLevel | Peer-reviewed dataset |
DatasetOrigin | Original dataset |
RepositorySupport | Unsupported dataset by repository |
PrimarySubmitter | Emmanuelle Mouton Barbosa |
SpeciesList | scientific name: Mus musculus (Mouse); NCBI TaxID: 10090; |
ModificationList | No PTMs are included in the dataset |
Instrument | timsTOF SCP |
Dataset History
Revision | Datetime | Status | ChangeLog Entry |
0 | 2023-07-25 03:32:15 | ID requested | |
⏵ 1 | 2024-09-24 02:08:48 | announced | |
Publication List
Dataset with its publication pending |
Keyword List
submitter keyword: E3 ubiquitin ligase, mouse Th2 cells,ASB2 |
Contact List
Odile Bruley Schiltz |
contact affiliation | Institut de Pharmacologie et de Biologie Structurale (IPBS), Université de Toulouse, CNRS, Université Toulouse III - Paul Sabatier (UT3), Toulouse, France |
contact email | Odile.Schiltz@ipbs.fr |
lab head | |
Emmanuelle Mouton Barbosa |
contact affiliation | IPBS CNRS |
contact email | emmanuelle.mouton@ipbs.fr |
dataset submitter | |
Full Dataset Link List
Dataset FTP location
NOTE: Most web browsers have now discontinued native support for FTP access within the browser window. But you can usually install another FTP app (we recommend FileZilla) and configure your browser to launch the external application when you click on this FTP link. Or otherwise, launch an app that supports FTP (like FileZilla) and use this address: ftp://ftp.pride.ebi.ac.uk/pride/data/archive/2024/09/PXD044062 |
PRIDE project URI |
Repository Record List
[ + ]
[ - ]
- PRIDE
- PXD044062
- Label: PRIDE project
- Name: Comparative analysis of the proteome of Th2 lymphocytes from WT or ASB2 KO mice