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PXD044062-1

PXD044062 is an original dataset announced via ProteomeXchange.

Dataset Summary
TitleComparative analysis of the proteome of Th2 lymphocytes from WT or ASB2 KO mice
DescriptionASB2α is an E3 ubiquitin ligase which is upregulated during Th2 differentiation of naive CD4+ T lymphocyte, and which is known to trigger ubiquitylation and proteasomal degradation of filamins (FLN) a and b. Because E3 ubiquitin ligases often ubiquitylate several substrates, we used an unbiased and broad mass spectrometry approach to identify ASB2α substrates in Th2 lymphocytes generated from naïve CD4+ T lymphocytes of control or ASB2 KO mice.
HostingRepositoryPRIDE
AnnounceDate2024-09-24
AnnouncementXMLSubmission_2024-09-24_02:08:47.908.xml
DigitalObjectIdentifier
ReviewLevelPeer-reviewed dataset
DatasetOriginOriginal dataset
RepositorySupportUnsupported dataset by repository
PrimarySubmitterEmmanuelle Mouton Barbosa
SpeciesList scientific name: Mus musculus (Mouse); NCBI TaxID: 10090;
ModificationListNo PTMs are included in the dataset
InstrumenttimsTOF SCP
Dataset History
RevisionDatetimeStatusChangeLog Entry
02023-07-25 03:32:15ID requested
12024-09-24 02:08:48announced
Publication List
Dataset with its publication pending
Keyword List
submitter keyword: E3 ubiquitin ligase, mouse Th2 cells,ASB2
Contact List
Odile Bruley Schiltz
contact affiliationInstitut de Pharmacologie et de Biologie Structurale (IPBS), Université de Toulouse, CNRS, Université Toulouse III - Paul Sabatier (UT3), Toulouse, France
contact emailOdile.Schiltz@ipbs.fr
lab head
Emmanuelle Mouton Barbosa
contact affiliationIPBS CNRS
contact emailemmanuelle.mouton@ipbs.fr
dataset submitter
Full Dataset Link List
Dataset FTP location
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PRIDE project URI
Repository Record List
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