PXD043978 is an
original dataset announced via ProteomeXchange.
Dataset Summary
| Title | Delineation of signaling networks that underlie differences in macrophage phenotypic states |
| Description | Quantitative proteomics and phosphoproteomics of primary human macrophages after exposure to different stimuli. Macrophages in the phenotypic states M1 (IFNγ + LPS), M2a (IL-4+IL-10), and M2c (IL-10) were characterized using global label-free LC-MS/MS quantification. |
| HostingRepository | PRIDE |
| AnnounceDate | 2025-11-24 |
| AnnouncementXML | Submission_2025-11-23_16:35:04.566.xml |
| DigitalObjectIdentifier | |
| ReviewLevel | Peer-reviewed dataset |
| DatasetOrigin | Original dataset |
| RepositorySupport | Unsupported dataset by repository |
| PrimarySubmitter | Jonas Bossart |
| SpeciesList | scientific name: Homo sapiens (Human); NCBI TaxID: NEWT:9606; |
| ModificationList | iodoacetamide derivatized residue |
| Instrument | Orbitrap Fusion Lumos |
Dataset History
| Revision | Datetime | Status | ChangeLog Entry |
|---|
| 0 | 2023-07-21 04:41:38 | ID requested | |
| ⏵ 1 | 2025-11-23 16:35:05 | announced | |
Publication List
| 10.1093/narmme/ugaf013; |
| Totu T, Bossart J, Caire E, Sribike K, Li C, Rottmar M, Sobottka B, Yu G, Ayala-Nunez V, Buljan M, Delineation of signaling routes that underlie differences in macrophage phenotypic states. NAR Mol Med, 2(2):ugaf013(2025) [pubmed] |
Keyword List
| submitter keyword: Human, Phosphoproteomics, Primary macrophages, Macrophage polarization, Proteomics, LC-MS/MS |
Contact List
| Marija Buljan |
|---|
| contact affiliation | Multi-omics for healthcare materials, Empa, Swiss Federal Laboratories for Materials Science and Technology |
| contact email | marija.buljan@empa.ch |
| lab head | |
| Jonas Bossart |
|---|
| contact affiliation | Multi-omics for healthcare materials, Empa, Swiss Federal Laboratories for Materials Science and Technology |
| contact email | jonas.bossart@empa.ch |
| dataset submitter | |
Full Dataset Link List
Dataset FTP location
NOTE: Most web browsers have now discontinued native support for FTP access within the browser window. But you can usually install another FTP app (we recommend FileZilla) and configure your browser to launch the external application when you click on this FTP link. Or otherwise, launch an app that supports FTP (like FileZilla) and use this address: ftp://ftp.pride.ebi.ac.uk/pride/data/archive/2025/11/PXD043978 |
| PRIDE project URI |
Repository Record List
[ + ]
[ - ]
- PRIDE
- PXD043978
- Label: PRIDE project
- Name: Delineation of signaling networks that underlie differences in macrophage phenotypic states
