PXD043791 is an
original dataset announced via ProteomeXchange.
Dataset Summary
| Title | Suppression of mitochondrial complex 1 in Drosophila melanogaster |
| Description | Aberrant mitochondrial function has been associated with an increasingly large number of human disease states. Observations from in vivo models where mitochondrial function is altered suggest that adaptations to mitochondrial dysfunction may underpin disease pathology. We hypothesized that the severity of these maladaptations could be shaped by the plasticity of the system when mitochondrial dysfunction manifests. To investigate this, we have used inducible fly models of mitochondrial complex I (CI) dysfunction to reduce mitochondrial function at two stages of the fly lifecycle, from early development and adult eclosion. |
| HostingRepository | PRIDE |
| AnnounceDate | 2025-01-15 |
| AnnouncementXML | Submission_2025-01-15_00:41:38.326.xml |
| DigitalObjectIdentifier | |
| ReviewLevel | Peer-reviewed dataset |
| DatasetOrigin | Original dataset |
| RepositorySupport | Unsupported dataset by repository |
| PrimarySubmitter | Yizhou Yu |
| SpeciesList | scientific name: Drosophila melanogaster (Fruit fly); NCBI TaxID: 7227; |
| ModificationList | No PTMs are included in the dataset |
| Instrument | Orbitrap Fusion |
Dataset History
| Revision | Datetime | Status | ChangeLog Entry |
|---|
| 0 | 2023-07-14 11:17:43 | ID requested | |
| ⏵ 1 | 2025-01-15 00:41:38 | announced | |
Publication List
| Dataset with its publication pending |
Keyword List
| submitter keyword: development,Drosophila melanogaster, mitochondrial complex 1 |
Contact List
| Luis Miguel Martins |
|---|
| contact affiliation | MRC Toxicology Unit, University of Cambridge |
| contact email | martins.lmiguel@gmail.com |
| lab head | |
| Yizhou Yu |
|---|
| contact affiliation | University of Cambridge |
| contact email | yizhou0421@gmail.com |
| dataset submitter | |
Full Dataset Link List
Dataset FTP location
NOTE: Most web browsers have now discontinued native support for FTP access within the browser window. But you can usually install another FTP app (we recommend FileZilla) and configure your browser to launch the external application when you click on this FTP link. Or otherwise, launch an app that supports FTP (like FileZilla) and use this address: ftp://ftp.pride.ebi.ac.uk/pride/data/archive/2025/01/PXD043791 |
| PRIDE project URI |
Repository Record List
[ + ]
[ - ]
- PRIDE
- PXD043791
- Label: PRIDE project
- Name: Suppression of mitochondrial complex 1 in Drosophila melanogaster
to receive all new ProteomeXchange dataset release announcements!
