PXD043781-2
PXD043781 is an original dataset announced via ProteomeXchange.
Dataset Summary
Title | Targeting USP8 inhibits O-GlcNAcylation of SLC7A11 to promote ferroptosis of hepatocellular carcinoma via stabilization of OGT |
Description | To explore the proteins that are potentially regulated by USP8, we performed immunoprecipitation-based mass spectrometry (IP-MS) following ectopic expression of Flag-USP8 and immunoprecipitation. We noticed that the O-Linked N-Acetylglucosamine (GlcNAc) Transferase (OGT) was immunoprecipitated by USP8 |
HostingRepository | iProX |
AnnounceDate | 2023-07-10 |
AnnouncementXML | Submission_2024-05-27_21:30:26.202.xml |
DigitalObjectIdentifier | |
ReviewLevel | Peer-reviewed dataset |
DatasetOrigin | Original dataset |
RepositorySupport | Unsupported dataset by repository |
PrimarySubmitter | Jianing Tang |
SpeciesList | scientific name: Homo sapiens; NCBI TaxID: 9606; |
ModificationList | phosphorylated residue |
Instrument | Q Exactive |
Dataset History
Revision | Datetime | Status | ChangeLog Entry |
---|---|---|---|
0 | 2023-07-14 00:24:48 | ID requested | |
1 | 2023-07-14 00:25:09 | announced | |
⏵ 2 | 2024-05-27 21:30:27 | announced | 2024-05-28: Update information. |
Publication List
Tang J, Long G, Hu K, Xiao D, Liu S, Xiao L, Zhou L, Tao Y, Targeting USP8 Inhibits O-GlcNAcylation of SLC7A11 to Promote Ferroptosis of Hepatocellular Carcinoma via Stabilization of OGT. Adv Sci (Weinh), 10(33):e2302953(2023) [pubmed] |
Keyword List
submitter keyword: USP8, OGT, liver cancer |
Contact List
Jianing Tang | |
---|---|
contact affiliation | Central South University |
contact email | TangJN@csu.edu.cn |
lab head | |
Jianing Tang | |
contact affiliation | Central South University |
contact email | TangJN@csu.edu.cn |
dataset submitter |
Full Dataset Link List
iProX dataset URI |