PXD043621-1

PXD043621 is an original dataset announced via ProteomeXchange.

Title	Multiple reaction monitoring based targeted validation of over-expressed proteins of high-grade gliomas
Description	High-grade gliomas (HGGs) are extremely aggressive primary brain tumors with high mortality rates. Despite notable advancements in clinical research, HGGs are still characterized by poor prognosis and appalling survival rates. Several global proteomics studies have reported many protein biomarkers however, the transition of these proteins biomarkers from lab to clinic is exceptionally low. In the current study, over-expressed HGG proteins identified from various global proteomics studies were validated in HGG tissue samples to explore their role as potential therapeutic candidates.
HostingRepository	PanoramaPublic
AnnounceDate	2024-08-01
AnnouncementXML	Submission_2024-08-01_10:58:19.469.xml
DigitalObjectIdentifier
ReviewLevel	Peer-reviewed dataset
DatasetOrigin	Original dataset
RepositorySupport	Supported dataset by repository
PrimarySubmitter	Ayushi Verma
SpeciesList	scientific name: Homo sapiens; NCBI TaxID: 9606;
ModificationList	Carbamidomethyl; Label:13C(6)15N(4)
Instrument	TSQ Altis

Revision	Datetime	Status	ChangeLog Entry
0	2023-07-08 15:12:44	ID requested
⏵ 1	2024-08-01 10:58:20	announced

Verma A, Patel R, Mahale A, Thorat RV, Rath SL, Sridhar E, Moiyadi A, Srivastava S, Drug Repurposing. OMICS, 28(2):59-75(2024) [pubmed]

submitter keyword: High-grade gliomas, glioblastoma, mass spectrometry, over-expressed protein markers, brain tumor

Sanjeeva Srivastava
contact affiliation	Department of Biosciences and Bioengineering, Indian Institute of Technology Bombay
contact email	sanjeeva@iitb.ac.in
lab head
Ayushi Verma
contact affiliation	Department of Biosciences and Bioengineering, Indian Institute of Technology Bombay
contact email	ayushi.verma228@gmail.com
dataset submitter

Panorama Public dataset URI