PXD043346-1

PXD043346 is an original dataset announced via ProteomeXchange.

Dataset Summary

Title	Menstrual blood derived mesenchymal stromal cells
Description	Mesenchymal stromal cells (MSCs) have been shown to exert their therapeutic effects through the secretion of various paracrine factors, including extracellular vesicles (EVs). These EVs are now being developed as a promising alternative to cell-based therapies. Menstrual blood-derived stromal cells (MenSCs) are a type of MSC that have emerged as a innovative source due to their immunomodulatory and regenerative properties. Additionally, new strategies of cell priming could potentially alter the concentration and cargo of released EVs, leading to modifications in their biological properties. In this study, we aimed to characterize the EVs released by MenSCs and to compare their therapeutic potential under three different preconditioning conditions (proinflammatory stimuli, physioxia, and acute hypoxia).
HostingRepository	MassIVE
AnnounceDate	2023-06-27
AnnouncementXML	Submission_2023-06-27_08:56:16.084.xml
DigitalObjectIdentifier
ReviewLevel	Non peer-reviewed dataset
DatasetOrigin	Original dataset
RepositorySupport	Unsupported dataset by repository
PrimarySubmitter	Witold Szymanski
SpeciesList	scientific name: Homo sapiens; common name: human; NCBI TaxID: 9606;
ModificationList	methionine oxidation with neutral loss of 64 Da; CarbamidomethylDTT; Deamidated:18O(1)
Instrument	timsTOF Pro

Dataset History

Revision	Datetime	Status	ChangeLog Entry
0	2023-06-27 08:53:34	ID requested
⏵ 1	2023-06-27 08:56:16	announced

Publication List

no publication

no publication

Keyword List

submitter keyword: Extracellular vesicles (EVs), exosomes, high-throughput proteomics, menstrual blood, mesenchymal stromal cells (MSCs), microvesicles, preconditioning

submitter keyword: Extracellular vesicles (EVs), exosomes, high-throughput proteomics, menstrual blood, mesenchymal stromal cells (MSCs), microvesicles, preconditioning

Contact List

Maria Gomez-Serrano
contact affiliation	Philipps University of Marburg
contact email	gomezser@staff.uni-marburg.de
lab head
Witold Szymanski
contact affiliation	Philipps-University Marburg Biochemical/Pharmacological Center Department of Medicine
contact email	witold.szymanski@uni-marburg.de
dataset submitter

Full Dataset Link List

MassIVE dataset URI
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MassIVE dataset URI

Dataset FTP location
NOTE: Most web browsers have now discontinued native support for FTP access within the browser window. But you can usually install another FTP app (we recommend FileZilla) and configure your browser to launch the external application when you click on this FTP link. Or otherwise, launch an app that supports FTP (like FileZilla) and use this address: ftp://massive.ucsd.edu/MSV000091644/