PXD043282-2

PXD043282 is an original dataset announced via ProteomeXchange.

Title	4D-diaXLMS: Proteome-wide Four-Dimensional Data-Independent Acquisition Workflow for Cross-linking Mass Spectrometry
Description	Cross-linking Mass Spectrometry (XL-MS) is a powerful tool for examining protein structures and interactions. Nevertheless, anal-ysis of low-abundance cross-linked peptides is often limited in data-dependent acquisition (DDA) mode due to its semistochastic nature. To address this issue, we introduced a workflow called 4D-diaXLMS, representing the first-ever application of four-dimensional data-independent acquisition for proteome-wide cross-linking analysis.
HostingRepository	iProX
AnnounceDate	2023-06-26
AnnouncementXML	Submission_2024-05-29_21:00:12.659.xml
DigitalObjectIdentifier
ReviewLevel	Peer-reviewed dataset
DatasetOrigin	Original dataset
RepositorySupport	Unsupported dataset by repository
PrimarySubmitter	Moran Chen
SpeciesList	scientific name: Homo sapiens; NCBI TaxID: 9606; scientific name: Saccharomyces cerevisiae; NCBI TaxID: 4932;
ModificationList	No PTMs are included in the dataset
Instrument	timsTOF Pro

Revision	Datetime	Status	ChangeLog Entry
0	2023-06-25 21:12:17	ID requested
1	2023-08-10 21:55:40	announced
⏵ 2	2024-05-29 21:00:13	announced	2024-05-30: Update information.

Hao Y, Chen M, Huang X, Xu H, Wu P, Chen S, 4D-diaXLMS: Proteome-wide Four-Dimensional Data-Independent Acquisition Workflow for Cross-Linking Mass Spectrometry. Anal Chem, 95(37):14077-14085(2023) [pubmed]

submitter keyword: diaPASEF, Crosslinking proteomics

Suming Chen
contact affiliation	The Institute for Advanced Studies, Wuhan University
contact email	sm.chen@whu.edu.cn
lab head
Moran Chen
contact affiliation	The Institute for Advanced Studies, Wuhan University
contact email	moran_chen123@qq.com
dataset submitter

iProX dataset URI