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PXD043123 is an original dataset announced via ProteomeXchange.

Dataset Summary
TitlePhenolic acid-induced phase separation and translation inhibition mediate plant interspecific competition
DescriptionPhenolic acids (PAs) secreted by donor plants suppress the growth of their susceptible plant neighbours. However, how structurally diverse ensembles of PAs are perceived by plants to mediate interspecific competition remains a mystery. Here, we show that a plant stress granule (SG) marker, RNA-BINDING PROTEIN 47B (RBP47B), is a sensor of PAs in Arabidopsis. PAs including salicylic acid (SA), 4-hydroxybenzoic acid, protocatechuic acid, etc. directly bind RBP47B, promote its phase separation and trigger SG formation accompanied by global translation inhibition. SA-induced global translation inhibition depends on RBP47 family members. RBP47s regulate the proteome rather than the absolute quantity of SG. The rbp47 quadruple mutant shows a reduced sensitivity to the inhibitory effect of the PA mixture as well as to that of PA-rich rice when tested in a co-culturing ecosystem. Our study discovers RBP47B as the long sought-after PA sensor and unveils PA-induced SG formation and translation inhibition as one of the PA perception mechanisms.
ReviewLevelPeer-reviewed dataset
DatasetOriginOriginal dataset
RepositorySupportUnsupported dataset by repository
PrimarySubmitterZhouli Xie
SpeciesList scientific name: Arabidopsis thaliana (Mouse-ear cress); NCBI TaxID: 3702;
ModificationListNo PTMs are included in the dataset
InstrumentOrbitrap Fusion Lumos
Dataset History
RevisionDatetimeStatusChangeLog Entry
02023-06-19 23:28:45ID requested
12023-08-28 17:56:21announced
22023-11-14 07:47:28announced2023-11-14: Updated project metadata.
Publication List
Dataset with its publication pending
Keyword List
submitter keyword: Salicylic acid (SA),Phenolic acid, Stress granules (SG), RNA-BINDING PROTEIN 47B (RBP47B)
Contact List
Wei Wang
contact affiliationState Key Laboratory for Protein and Plant Gene Research, School of Life Sciences, Peking University, Beijing, China
contact emailoneway1985@pku.edu.cn
lab head
Zhouli Xie
contact affiliationPeking University
contact emailzhou_lixie@126.com
dataset submitter
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Dataset FTP location
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