PXD042994-1

PXD042994 is an original dataset announced via ProteomeXchange.

Title	Altered GM1 catabolism affects NMDAR-mediated Ca2+ signaling at ER-PM junctions and increases synaptic spine formation
Description	GM1-ganglioside, an abundant GSL in neuronal membranes, is integral to ER-PM junctions where it interacts with synaptic proteins/receptors and regulates Ca2+ signaling.
HostingRepository	PRIDE
AnnounceDate	2024-03-19
AnnouncementXML	Submission_2024-03-19_15:57:53.171.xml
DigitalObjectIdentifier
ReviewLevel	Peer-reviewed dataset
DatasetOrigin	Original dataset
RepositorySupport	Unsupported dataset by repository
PrimarySubmitter	Ashutosh Mishra
SpeciesList	scientific name: Mus musculus (Mouse); NCBI TaxID: 10090;
ModificationList	No PTMs are included in the dataset
Instrument	Orbitrap Fusion

Revision	Datetime	Status	ChangeLog Entry
0	2023-06-14 15:00:01	ID requested
⏵ 1	2024-03-19 15:57:53	announced

Dataset with its publication pending

submitter keyword: membrane contact sites (MCS), glycosphingolipids (GSLs), Proteomics

Alessandra D'Azzo-Grosveld
contact affiliation	Member, St. Jude Faculty Jewelers For Children Endowed Chair in Genetics and Gene Therapy
contact email	sandra.dazzo@stjude.org
lab head
Ashutosh Mishra
contact affiliation	St. Jude Children's Research Hospital
contact email	ashutosh.mishra@stjude.org
dataset submitter

Dataset FTP location NOTE: Most web browsers have now discontinued native support for FTP access within the browser window. But you can usually install another FTP app (we recommend FileZilla) and configure your browser to launch the external application when you click on this FTP link. Or otherwise, launch an app that supports FTP (like FileZilla) and use this address: ftp://ftp.pride.ebi.ac.uk/pride/data/archive/2024/03/PXD042994

PRIDE project URI

• PRIDE
  1. PXD042994
     1. Label: PRIDE project
     2. Name: Altered GM1 catabolism affects NMDAR-mediated Ca2+ signaling at ER-PM junctions and increases synaptic spine formation