PXD042921-2

PXD042921 is an original dataset announced via ProteomeXchange.

Title	5xFAD transgenic mouse Abeta proteoforms
Description	In this study, we have evaluated amyloidosis-relevant Aβ proteoform flux using immunoenrichment and quantitative Top-Down Mass Spectrometry in a well-studied 5xFAD mouse model of age-dependent Aβ amyloidosis.
HostingRepository	PRIDE
AnnounceDate	2024-10-22
AnnouncementXML	Submission_2024-10-22_06:03:57.209.xml
DigitalObjectIdentifier
ReviewLevel	Peer-reviewed dataset
DatasetOrigin	Original dataset
RepositorySupport	Unsupported dataset by repository
PrimarySubmitter	Soumya Kandi
SpeciesList	scientific name: Mus musculus (Mouse); NCBI TaxID: 10090;
ModificationList	dihydroxylated residue; phosphorylated residue; hexose glycated L-lysine; monohydroxylated residue
Instrument	Orbitrap Fusion Lumos

Revision	Datetime	Status	ChangeLog Entry
0	2023-06-12 19:16:01	ID requested
1	2023-09-26 22:07:26	announced
⏵ 2	2024-10-22 06:03:57	announced	2024-10-22: Updated project metadata.

Dataset with its publication pending

submitter keyword: Amyloid beta, Alzheimer’s Disease, transgenic mouse model, 5xFAD, Top-Down Mass Spectrometry

Steven Patrie
contact affiliation	Northwestern University
contact email	steven.patrie@northwestern.edu
lab head
Soumya Kandi
contact affiliation	Northwestern University
contact email	Soumyakandi2023@u.northwestern.edu
dataset submitter

Dataset FTP location NOTE: Most web browsers have now discontinued native support for FTP access within the browser window. But you can usually install another FTP app (we recommend FileZilla) and configure your browser to launch the external application when you click on this FTP link. Or otherwise, launch an app that supports FTP (like FileZilla) and use this address: ftp://ftp.pride.ebi.ac.uk/pride/data/archive/2023/09/PXD042921

PRIDE project URI

• PRIDE
  1. PXD042921
     1. Label: PRIDE project
     2. Name: 5xFAD transgenic mouse Abeta proteoforms