PXD042668 is an
original dataset announced via ProteomeXchange.
Dataset Summary
Title | Protein Extraction from Ancient Teeth and Dental Calculus Compatible with Subsequent DNA Extraction |
Description | Dental calculus is becoming a crucial material in the study of past populations, with increasing interest in its proteomic and genomic content. Here we suggest further development of protocol for analysis of ancient proteins and a combined approach for subsequent ancient DNA extraction. We tested the protocol on recent teeth. We then applied the optimised protocol to ancient teeth to limit the destruction of calculus, as it is a precious and irreplaceable source of dietary, microbiological, and ecological information in the archaeological context. Finally, the applicability of the protocol was proven on samples of ancient calculus. |
HostingRepository | PRIDE |
AnnounceDate | 2023-11-14 |
AnnouncementXML | Submission_2023-11-14_08:28:29.401.xml |
DigitalObjectIdentifier | |
ReviewLevel | Peer-reviewed dataset |
DatasetOrigin | Original dataset |
RepositorySupport | Unsupported dataset by repository |
PrimarySubmitter | Pavel Roudnický |
SpeciesList | scientific name: Homo sapiens (Human); NCBI TaxID: 9606; |
ModificationList | monohydroxylated residue; deamidated residue; iodoacetamide derivatized residue |
Instrument | timsTOF Pro; Orbitrap Fusion Lumos |
Dataset History
Revision | Datetime | Status | ChangeLog Entry |
0 | 2023-06-02 07:34:04 | ID requested | |
1 | 2023-09-11 00:24:12 | announced | |
⏵ 2 | 2023-11-14 08:28:29 | announced | 2023-11-14: Updated project metadata. |
Publication List
Dataset with its publication pending |
Keyword List
submitter keyword: protein extraction, palaeoproteomics, ancient DNA, ancient proteins, dental calculus,bioarchaeology |
Contact List
Zbyněk Zdráhal |
contact affiliation | Proteomics Core Facility and Research Group Proteomics, CEITEC-MU, Masaryk University, Brno, Czech Republic |
contact email | zdrahal@sci.muni.cz |
lab head | |
Pavel Roudnický |
contact affiliation | Masaryk University |
contact email | p.roudnicky@mail.muni.cz |
dataset submitter | |
Full Dataset Link List
Dataset FTP location
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PRIDE project URI |
Repository Record List
[ + ]
[ - ]
- PRIDE
- PXD042668
- Label: PRIDE project
- Name: Protein Extraction from Ancient Teeth and Dental Calculus Compatible with Subsequent DNA Extraction