PXD042631 is an
original dataset announced via ProteomeXchange.
Dataset Summary
Title | Proteomic Profiling of PPIX-binding proteins between cell types |
Description | To use a probe connecting PPIX with biotin to affinity purify interacting proteins in various cell lines. Then to use TMT labeling of the purified proteins, as well as those from controls, to construct data sets of proteins identified with mass spec, together with biostatistical analysis, to distinguish valid interactions for further study. These data may cumulatively allow us to delineate trafficking, signaling, or metabolic pathways related to PPIX binding. |
HostingRepository | PRIDE |
AnnounceDate | 2023-11-14 |
AnnouncementXML | Submission_2023-11-14_09:03:44.178.xml |
DigitalObjectIdentifier | |
ReviewLevel | Peer-reviewed dataset |
DatasetOrigin | Original dataset |
RepositorySupport | Unsupported dataset by repository |
PrimarySubmitter | Zuo-Fei Yuan |
SpeciesList | scientific name: Mus musculus (Mouse); NCBI TaxID: 10090; scientific name: Homo sapiens (Human); NCBI TaxID: 9606; |
ModificationList | No PTMs are included in the dataset |
Instrument | Orbitrap Fusion |
Dataset History
Revision | Datetime | Status | ChangeLog Entry |
0 | 2023-06-01 15:26:25 | ID requested | |
1 | 2023-07-20 12:07:27 | announced | |
⏵ 2 | 2023-11-14 09:03:48 | announced | 2023-11-14: Updated project metadata. |
Publication List
Lynch J, Wang Y, Li Y, Kavdia K, Fukuda Y, Ranjit S, Robinson CG, Grace CR, Xia Y, Peng J, Schuetz JD, A PPIX-binding probe facilitates discovery of PPIX-induced cell death modulation by peroxiredoxin. Commun Biol, 6(1):673(2023) [pubmed] |
Keyword List
submitter keyword: ferroptosis, TMT, PRDX3, reactive oxygen species.,Protoporphyrin IX |
Contact List
John Schuetz |
contact affiliation | Department of Pharmaceutical Sciences, St. Jude Children's Research Hospital, Memphis, TN 38105, USA |
contact email | John.Schuetz@stjude.org |
lab head | |
Zuo-Fei Yuan |
contact affiliation | St. Jude Children's Research Hospital |
contact email | zuo-fei.yuan@stjude.org |
dataset submitter | |
Full Dataset Link List
Dataset FTP location
NOTE: Most web browsers have now discontinued native support for FTP access within the browser window. But you can usually install another FTP app (we recommend FileZilla) and configure your browser to launch the external application when you click on this FTP link. Or otherwise, launch an app that supports FTP (like FileZilla) and use this address: ftp://ftp.pride.ebi.ac.uk/pride/data/archive/2023/07/PXD042631 |
PRIDE project URI |
Repository Record List
[ + ]
[ - ]
- PRIDE
- PXD042631
- Label: PRIDE project
- Name: Proteomic Profiling of PPIX-binding proteins between cell types