PXD042618-2

PXD042618 is an original dataset announced via ProteomeXchange.

Title	Human nasal epithelial cell, Influenza virus, iTRAQ
Description	Few studies have examined the local surface remodeling of primary human nasal epithelial cells (HNECs) during viral infection. Hence, the full range of upregulated adhesion molecules during respiratory viral infections that facilitate bacterial attachment and entry remain unknown. Accordingly, the current study provides a comprehensive view of HNEC responses to influenza virus pH1N1 infection, via global proteome profiling of uninfected (Mock, n = 4) and influenza-infected (Virus-only, n = 4) HNECs with isobaric tags using relative and absolute quantitation (iTRAQ) technique. A total of 3583 proteins were detected, 89 of which were significantly increased (52 proteins) or decreased (37 proteins) in the virus-infected HNECs compared to mock-infected controls (p < 0.05).
HostingRepository	PRIDE
AnnounceDate	2024-10-22
AnnouncementXML	Submission_2024-10-22_06:38:30.228.xml
DigitalObjectIdentifier
ReviewLevel	Peer-reviewed dataset
DatasetOrigin	Original dataset
RepositorySupport	Unsupported dataset by repository
PrimarySubmitter	Youn Wook Chung
SpeciesList	scientific name: Homo sapiens (Human); NCBI TaxID: 9606;
ModificationList	No PTMs are included in the dataset
Instrument	LTQ Orbitrap Velos

Revision	Datetime	Status	ChangeLog Entry
0	2023-06-01 07:31:28	ID requested
1	2024-05-07 22:51:21	announced
⏵ 2	2024-10-22 06:38:30	announced	2024-10-22: Updated project metadata.

10.1038/S41467-024-47963-5;

submitter keyword: Human nasal epithelial cell, Influenza virus, iTRAQ

Ji-Hwan Ryu
contact affiliation	Severance Biomedical Science Institute, Yonsei University College of Medicine
contact email	yjh@yuhs.ac
lab head
Youn Wook Chung
contact affiliation	Severance Biomedical Science Institute, Yonsei University College of Medicine
contact email	chungyw@yuhs.ac
dataset submitter

Dataset FTP location NOTE: Most web browsers have now discontinued native support for FTP access within the browser window. But you can usually install another FTP app (we recommend FileZilla) and configure your browser to launch the external application when you click on this FTP link. Or otherwise, launch an app that supports FTP (like FileZilla) and use this address: ftp://ftp.pride.ebi.ac.uk/pride/data/archive/2024/05/PXD042618

PRIDE project URI

• PRIDE
  1. PXD042618
     1. Label: PRIDE project
     2. Name: Human nasal epithelial cell, Influenza virus, iTRAQ