PXD042567-1

PXD042567 is an original dataset announced via ProteomeXchange.

Dataset Summary

Title	The Cystatin D Interactome Associated to Systemic Mastocytosis
Description	he aim of the project is to characterize qualitatively and quantitatively the interaction of cystatin D in other protein partner and the formation of a complex in whole saliva of patients affected by different forms of systemic mastocytosis (SM), with and without skin involvement. The different composition of the complex could be useful to distinguish patients from healthy subject and the different forms of systemic mastocytosis. Pools of whole saliva from SM (SM-C and SM+C) patients, and from sex/age matched healthy controls were submitted to immunoprecipitation assay using cystatin D antibody followed by SDS-PAGE in reducing conditions, tryptic digestion, and nano-HPLC-high-resolution-MS/MS analysis.
HostingRepository	PRIDE
AnnounceDate	2023-10-24
AnnouncementXML	Submission_2023-10-24_13:14:07.294.xml
DigitalObjectIdentifier
ReviewLevel	Peer-reviewed dataset
DatasetOrigin	Original dataset
RepositorySupport	Unsupported dataset by repository
PrimarySubmitter	SimoneSerrao
SpeciesList	scientific name: Homo sapiens (Human); NCBI TaxID: 9606;
ModificationList	phosphorylated residue; Oxidation of proline (to glutamic acid); acetylated residue; monohydroxylated residue; iodoacetamide derivatized residue
Instrument	LTQ Orbitrap Elite

Dataset History

Revision	Datetime	Status	ChangeLog Entry
0	2023-05-31 01:22:10	ID requested
⏵ 1	2023-10-24 13:14:09	announced
2	2023-11-14 09:11:49	announced	2023-11-14: Updated project metadata.
3	2024-10-22 06:12:14	announced	2024-10-22: Updated project metadata.

Publication List

Serrao S, Contini C, Guadalupi G, Olianas A, Lai G, Messana I, Castagnola M, Costanzo G, Firinu D, Del Giacco S, Manconi B, Cabras T, Salivary Cystatin D Interactome in Patients with Systemic Mastocytosis: An Exploratory Study. Int J Mol Sci, 24(19):(2023) [pubmed]

Serrao S, Contini C, Guadalupi G, Olianas A, Lai G, Messana I, Castagnola M, Costanzo G, Firinu D, Del Giacco S, Manconi B, Cabras T, Salivary Cystatin D Interactome in Patients with Systemic Mastocytosis: An Exploratory Study. Int J Mol Sci, 24(19):(2023) [pubmed]

Keyword List

submitter keyword: Mastocytosis
High-resolution Mass Spectrometry
Immunoprecipitation assay
Cystatin D

submitter keyword: Mastocytosis

High-resolution Mass Spectrometry

Immunoprecipitation assay

Cystatin D

Contact List

Professor TizianaCabras
contact affiliation	Life and Environmental Sciences Department (Biomedical Section) - University of Cagliari
contact email	tcabras@unica.it
lab head
SimoneSerrao
contact affiliation	Life and Environmental Sciences Department (Biomedical Section) - University of Cagliari
contact email	simone.serrao@unica.it
dataset submitter

Full Dataset Link List

Dataset FTP location NOTE: Most web browsers have now discontinued native support for FTP access within the browser window. But you can usually install another FTP app (we recommend FileZilla) and configure your browser to launch the external application when you click on this FTP link. Or otherwise, launch an app that supports FTP (like FileZilla) and use this address: ftp://ftp.pride.ebi.ac.uk/pride/data/archive/2023/10/PXD042567
PRIDE project URI

Dataset FTP location
NOTE: Most web browsers have now discontinued native support for FTP access within the browser window. But you can usually install another FTP app (we recommend FileZilla) and configure your browser to launch the external application when you click on this FTP link. Or otherwise, launch an app that supports FTP (like FileZilla) and use this address: ftp://ftp.pride.ebi.ac.uk/pride/data/archive/2023/10/PXD042567

PRIDE project URI

Repository Record List

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