PXD042380-2

PXD042380 is an original dataset announced via ProteomeXchange.

Title	Proteomics of Triple Negative Breast Cancer Cells Treated with SU056
Description	1. Quantitative Proteomics: MDA-MB-231, MDA-MB-468, and MCF12A cells were treated with DMSO (vehicle control) or SU056 (novel small molecule drug candidate). Quantitative proteomics analysis was performed on cell lysates. 2. Cellular Thermal Shift Assay (CETSA): MDA-MB-231 cells were treated with DMSO or SU056 and incubated at different temperatures and protein differences in the resulting soluble and insoluble fractions were determined. 3. Cellular Thermal Shift Assay (CETSA): MDA-MB-231 YBOX1 KD cells were treated with DMSO or SU056 and incubated at different temperatures and protein differences in the soluble fractions were determined.
HostingRepository	PRIDE
AnnounceDate	2024-10-22
AnnouncementXML	Submission_2024-10-22_06:35:09.948.xml
DigitalObjectIdentifier
ReviewLevel	Peer-reviewed dataset
DatasetOrigin	Original dataset
RepositorySupport	Unsupported dataset by repository
PrimarySubmitter	Sharon Pitteri
SpeciesList	scientific name: Homo sapiens (Human); NCBI TaxID: 9606;
ModificationList	TMT6plex-126 reporter+balance reagent acylated residue; iodoacetamide derivatized residue
Instrument	Orbitrap Eclipse; LTQ Orbitrap Elite

Revision	Datetime	Status	ChangeLog Entry
0	2023-05-21 22:38:55	ID requested
1	2024-04-04 09:20:31	announced
⏵ 2	2024-10-22 06:35:10	announced	2024-10-22: Updated project metadata.

Dataset with its publication pending

submitter keyword: breast cancer, cell lines, triple negative, treatment

Sharon Pitteri
contact affiliation	Department of Radiology Canary Center at Stanford for Cancer Early Detection Stanford School of Medicine Stanford University
contact email	spitteri@stanford.edu
lab head
Sharon Pitteri
contact affiliation	Stanford University
contact email	spitteri@stanford.edu
dataset submitter

Dataset FTP location NOTE: Most web browsers have now discontinued native support for FTP access within the browser window. But you can usually install another FTP app (we recommend FileZilla) and configure your browser to launch the external application when you click on this FTP link. Or otherwise, launch an app that supports FTP (like FileZilla) and use this address: ftp://ftp.pride.ebi.ac.uk/pride/data/archive/2024/04/PXD042380

PRIDE project URI

• PRIDE
  1. PXD042380
     1. Label: PRIDE project
     2. Name: Proteomics of Triple Negative Breast Cancer Cells Treated with SU056