PXD042365-2

PXD042365 is an original dataset announced via ProteomeXchange.

Title	Secretome profiling of Artemisia absinthium extract loaded polymeric nanoparticles-treated MCF-7 and MDA MB-231 cell lines.
Description	Temperature and pH-sensitive, self-assembled polymeric nanoparticles, made of N-isopropyl acrylamide (NIPAAM), N-vinyl pyrrolidone (VP), and acrylic acid (AA) are biocompatible and have been used in the past with several drugs for site-specific delivery of different formulations. In the present study, the nano LC-MS/MS proteomic approach was employed to compare the secretome of Artemisia absinthium extract loaded polymeric nanoparticles-treated MCF-7 and MDA MB-231 cell lines targeted against the tumor microenvironment and comparison with corresponding untreated cell lines as a control to identify potential therapeutic targets and easily-accessible biomarkers among differentially expressed secretory proteins.
HostingRepository	PRIDE
AnnounceDate	2023-11-14
AnnouncementXML	Submission_2023-11-14_07:54:32.839.xml
DigitalObjectIdentifier
ReviewLevel	Peer-reviewed dataset
DatasetOrigin	Original dataset
RepositorySupport	Unsupported dataset by repository
PrimarySubmitter	SAIMA WAJID
SpeciesList	scientific name: Homo sapiens (Human); NCBI TaxID: 9606;
ModificationList	acetylated residue; monohydroxylated residue; iodoacetamide derivatized residue
Instrument	Q Exactive

Revision	Datetime	Status	ChangeLog Entry
0	2023-05-20 03:04:02	ID requested
1	2023-08-29 04:30:47	announced
⏵ 2	2023-11-14 07:54:33	announced	2023-11-14: Updated project metadata.
3	2024-10-22 06:02:04	announced	2024-10-22: Updated project metadata.

Dataset with its publication pending

submitter keyword: Artemisia absinthium, MDA MB-231, Polymeric nanoparticles,MCF-7, LC-MS/MS

Saima Wajid
contact affiliation	Department of Biotechnology, School of Chemical & Life Sciences, Jamia Hamdard, Hamdard Nagar, New Delhi, 110062, India
contact email	swajid@jamiahamdard.ac.in
lab head
SAIMA WAJID
contact affiliation	Department of Biotechnology, School of Chemical & Life Sciences, Jamia Hamdard, Hamdard Nagar, New Delhi, 110062.
contact email	swajid@jamiahamdard.ac.in
dataset submitter

Dataset FTP location NOTE: Most web browsers have now discontinued native support for FTP access within the browser window. But you can usually install another FTP app (we recommend FileZilla) and configure your browser to launch the external application when you click on this FTP link. Or otherwise, launch an app that supports FTP (like FileZilla) and use this address: ftp://ftp.pride.ebi.ac.uk/pride/data/archive/2023/08/PXD042365

PRIDE project URI

• PRIDE
  1. PXD042365
     1. Label: PRIDE project
     2. Name: Secretome profiling of Artemisia absinthium extract loaded polymeric nanoparticles-treated MCF-7 and MDA MB-231 cell lines.