PXD042344-2

PXD042344 is an original dataset announced via ProteomeXchange.

Dataset Summary

Title	Microglia and brain organoids
Description	iPSC-derived microglia export cholesterol to neuronal cells in human brain organoids and promote their maturation
HostingRepository	jPOST
AnnounceDate	2023-05-19
AnnouncementXML	Submission_2023-11-22_23:21:09.750.xml
DigitalObjectIdentifier
ReviewLevel	Peer-reviewed dataset
DatasetOrigin	Original dataset
RepositorySupport	Unsupported dataset by repository
PrimarySubmitter	Radoslaw Sobota
SpeciesList	scientific name: Homo sapiens (Human); NCBI TaxID: 9606;
ModificationList	S-carboxamidomethyl-L-cysteine; L-methionine sulfoxide; alpha-amino acetylated residue; deamidated L-glutamine; deamidated L-asparagine
Instrument	instrument

Dataset History

Revision	Datetime	Status	ChangeLog Entry
0	2023-05-18 14:46:39	ID requested
1	2023-05-18 14:48:57	announced
⏵ 2	2023-11-22 23:21:12	announced	2023-11-23: Updated PubMed.

Publication List

Park DS, Kozaki T, Tiwari SK, Moreira M, Khalilnezhad A, Torta F, Olivi, é N, Thiam CH, Liani O, Silvin A, Phoo WW, Gao L, Triebl A, Tham WK, Gon, ç, alves L, Kong WT, Raman S, Zhang XM, Dunsmore G, Dutertre CA, Lee S, Ong JM, Balachander A, Khalilnezhad S, Lum J, Duan K, Lim ZM, Tan L, Low I, Utami KH, Yeo XY, Di Tommaso S, Dupuy JW, Varga B, Karadottir RT, Madathummal MC, Bonne I, Malleret B, Binte ZY, Wei Da N, Tan Y, Wong WJ, Zhang J, Chen J, Sobota RM, Howland SW, Ng LG, Saltel F, Castel D, Grill J, Minard V, Albani S, Chan JKY, Thion MS, Jung SY, Wenk MR, Pouladi MA, Pasqualini C, Angeli V, Cexus ONF, Ginhoux F, iPS-cell-derived microglia promote brain organoid maturation via cholesterol transfer. Nature, 623(7986):397-405(2023) [pubmed]

Park DS, Kozaki T, Tiwari SK, Moreira M, Khalilnezhad A, Torta F, Olivi, é N, Thiam CH, Liani O, Silvin A, Phoo WW, Gao L, Triebl A, Tham WK, Gon, ç, alves L, Kong WT, Raman S, Zhang XM, Dunsmore G, Dutertre CA, Lee S, Ong JM, Balachander A, Khalilnezhad S, Lum J, Duan K, Lim ZM, Tan L, Low I, Utami KH, Yeo XY, Di Tommaso S, Dupuy JW, Varga B, Karadottir RT, Madathummal MC, Bonne I, Malleret B, Binte ZY, Wei Da N, Tan Y, Wong WJ, Zhang J, Chen J, Sobota RM, Howland SW, Ng LG, Saltel F, Castel D, Grill J, Minard V, Albani S, Chan JKY, Thion MS, Jung SY, Wenk MR, Pouladi MA, Pasqualini C, Angeli V, Cexus ONF, Ginhoux F, iPS-cell-derived microglia promote brain organoid maturation via cholesterol transfer. Nature, 623(7986):397-405(2023) [pubmed]

Keyword List

submitter keyword: LFQ, brain organoids, microglia

submitter keyword: LFQ, brain organoids, microglia

Contact List

Florent Ginhoux
lab head
Radoslaw Sobota
contact affiliation	IMCB A-STAR Singapore
dataset submitter

Full Dataset Link List

jPOST dataset URI
Dataset FTP location NOTE: Most web browsers have now discontinued native support for FTP access within the browser window. But you can usually install another FTP app (we recommend FileZilla) and configure your browser to launch the external application when you click on this FTP link. Or otherwise, launch an app that supports FTP (like FileZilla) and use this address: ftp://ftp.jpostdb.org/JPST001822/

jPOST dataset URI

Dataset FTP location
NOTE: Most web browsers have now discontinued native support for FTP access within the browser window. But you can usually install another FTP app (we recommend FileZilla) and configure your browser to launch the external application when you click on this FTP link. Or otherwise, launch an app that supports FTP (like FileZilla) and use this address: ftp://ftp.jpostdb.org/JPST001822/