PXD042271-2

PXD042271 is an original dataset announced via ProteomeXchange.

Dataset Summary

Title	human HEK293T S9.6 Mass spectrometry
Description	We are interested in proteins which could preferentially interact with DNA: RNA hybrids upon DNA damage. To achieve that, we treated HEK293T with 10 Gy IR, followed by 20 min recovery. We applied S9.6 antibody, which could recognize DNA: RNA hybrids structure, to isolate their interactome upon either normal conditions or DNA damage conditions, after which those proteins sample were sent for mass spec analysis, and proteins specifically interacting with DNA: RNA hybrids were then screened and analysed.
HostingRepository	PRIDE
AnnounceDate	2024-10-22
AnnouncementXML	Submission_2024-10-22_06:36:23.776.xml
DigitalObjectIdentifier
ReviewLevel	Peer-reviewed dataset
DatasetOrigin	Original dataset
RepositorySupport	Unsupported dataset by repository
PrimarySubmitter	Kamal Ajit
SpeciesList	scientific name: Homo sapiens (Human); NCBI TaxID: 9606;
ModificationList	No PTMs are included in the dataset
Instrument	Q Exactive HF; Q Exactive

Dataset History

Revision	Datetime	Status	ChangeLog Entry
0	2023-05-16 12:07:11	ID requested
1	2024-04-17 03:08:19	announced
⏵ 2	2024-10-22 06:36:24	announced	2024-10-22: Updated project metadata.

Publication List

10.1101/2024.02.19.581003;

10.1101/2024.02.19.581003;

Keyword List

submitter keyword: DNA: RNA hybrids, S9.6, HEK293T cells,human

submitter keyword: DNA: RNA hybrids, S9.6, HEK293T cells,human

Contact List

Prof Monika Gullerova
contact affiliation	Sir William Dunn School of Pathology University of Oxford
contact email	monika.gullerova@path.ox.ac.uk
lab head
Kamal Ajit
contact affiliation	University of Oxford
contact email	kamal.ajit@path.ox.ac.uk
dataset submitter

Full Dataset Link List

Dataset FTP location NOTE: Most web browsers have now discontinued native support for FTP access within the browser window. But you can usually install another FTP app (we recommend FileZilla) and configure your browser to launch the external application when you click on this FTP link. Or otherwise, launch an app that supports FTP (like FileZilla) and use this address: ftp://ftp.pride.ebi.ac.uk/pride/data/archive/2024/04/PXD042271
PRIDE project URI

Dataset FTP location
NOTE: Most web browsers have now discontinued native support for FTP access within the browser window. But you can usually install another FTP app (we recommend FileZilla) and configure your browser to launch the external application when you click on this FTP link. Or otherwise, launch an app that supports FTP (like FileZilla) and use this address: ftp://ftp.pride.ebi.ac.uk/pride/data/archive/2024/04/PXD042271

PRIDE project URI

Repository Record List

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