PXD042137 is an
original dataset announced via ProteomeXchange.
Dataset Summary
Title | N-glycoproteomics and SESTAR++ analysis based on SeMOE |
Description | The isotopic envelope pattern of selenium is guaranteed by its six stable isotopes with distinctive distribution (74Se, 0.89%; 76Se, 9.37%; 77Se, 7.63%; 78Se, 23.77%; 80Se, 49.61%; 82Se, 8.73%). We postulated that the effective incorporation of selenosugar in glycoproteins would achieve direct isotopic pattern prediction for glycopeptides, without the need for secondary tagging procedures. Consequently, we performed comparative studies using a previously reported computational algorithm, the updated version of selenium-encoded isotopic signature targeted profiling (SESTAR++)31, 32, and a glycan-first glycopeptide search engine, pGlyco3 to comprehensively analyze the intact N-glycopeptides in cells treated with SeMOE probes. |
HostingRepository | PRIDE |
AnnounceDate | 2023-11-20 |
AnnouncementXML | Submission_2023-11-20_00:06:11.543.xml |
DigitalObjectIdentifier | |
ReviewLevel | Peer-reviewed dataset |
DatasetOrigin | Original dataset |
RepositorySupport | Unsupported dataset by repository |
PrimarySubmitter | Xiao Tian |
SpeciesList | scientific name: Homo sapiens (Human); NCBI TaxID: 9606; |
ModificationList | complex glycosylation |
Instrument | Orbitrap Fusion Lumos |
Dataset History
Revision | Datetime | Status | ChangeLog Entry |
0 | 2023-05-11 01:02:00 | ID requested | |
⏵ 1 | 2023-11-20 00:06:11 | announced | |
Publication List
Dataset with its publication pending |
Keyword List
submitter keyword: Human, N-glycoproteomics, HeLa cell, SESTAR, SeMOE |
Contact List
Ran Xie |
contact affiliation | State Key Laboratory of Coordination Chemistry, School of Chemistry and Chemical Engineering, Chemistry and Biomedicine Innovation Center (ChemBIC), Nanjing University, Nanjing, China |
contact email | ranxie@nju.edu.cn |
lab head | |
Xiao Tian |
contact affiliation | Nanjing University |
contact email | tianxiao150200@163.com |
dataset submitter | |
Full Dataset Link List
Dataset FTP location
NOTE: Most web browsers have now discontinued native support for FTP access within the browser window. But you can usually install another FTP app (we recommend FileZilla) and configure your browser to launch the external application when you click on this FTP link. Or otherwise, launch an app that supports FTP (like FileZilla) and use this address: ftp://ftp.pride.ebi.ac.uk/pride/data/archive/2023/11/PXD042137 |
PRIDE project URI |
Repository Record List
[ + ]
[ - ]
- PRIDE
- PXD042137
- Label: PRIDE project
- Name: N-glycoproteomics and SESTAR++ analysis based on SeMOE