PXD041959-1
PXD041959 is an original dataset announced via ProteomeXchange.
Dataset Summary
| Title | MCF7_CDKi_globalproteomics_phosphoproteomics |
| Description | Proteomic and phosphoproteomic analysis of MCF7 cells treated with Palbociclib (CDK4/6 inhibitor), PF3600 (CDK2 inhibitor) or both for 1 hour and 24 hours. 'P_1_1' P refers to phosphoproteomic analysis. Otherwise, global proteomics was performed. Number (1,2,3) refers to the run number. 3 runs were performed. Samples were TMT labelled and in each run there were the following samples: DMSO 1 h, DMSO 24 h, 1uM Palbociclib 25nM PF3600 1 h, 1uM Palbociclib 25nM PF3600 24 h, 1uM Palbociclib 1 h, 1uM Palbociclib 24 h, 25nM PF3600 1 h, 25nM PF3600 24 h. Number (1-24 for P or 1-12 for global) refers to the fraction. |
| HostingRepository | MassIVE |
| AnnounceDate | 2023-05-25 |
| AnnouncementXML | Submission_2023-05-25_16:27:02.809.xml |
| DigitalObjectIdentifier | |
| ReviewLevel | Non peer-reviewed dataset |
| DatasetOrigin | Original dataset |
| RepositorySupport | Unsupported dataset by repository |
| PrimarySubmitter | Lotte Watts |
| SpeciesList | scientific name: Homo sapiens; common name: human; NCBI TaxID: 9606; |
| ModificationList | O-phospho-L-serine; O-phospho-L-threonine; O4'-phospho-L-tyrosine; L-methionine sulfoxide; unknown modification; S-carboxamidomethyl-L-cysteine |
| Instrument | Orbitrap Fusion Lumos |
Dataset History
| Revision | Datetime | Status | ChangeLog Entry |
|---|---|---|---|
| 0 | 2023-05-03 17:37:41 | ID requested | |
| ⏵ 1 | 2023-05-25 16:27:03 | announced |
Publication List
| no publication |
Keyword List
| submitter keyword: CDK inhibitors, CDK2, CDK4/6, MCF7, Breast Cancer |
Contact List
| John Lapek | |
|---|---|
| contact affiliation | Belharra Therapeutics |
| contact email | jlapek@belharratx.com |
| lab head | |
| Lotte Watts | |
| contact affiliation | University of Colorado |
| contact email | lotte.watts@colorado.edu |
| dataset submitter | |
Full Dataset Link List
| MassIVE dataset URI |
| Dataset FTP location NOTE: Most web browsers have now discontinued native support for FTP access within the browser window. But you can usually install another FTP app (we recommend FileZilla) and configure your browser to launch the external application when you click on this FTP link. Or otherwise, launch an app that supports FTP (like FileZilla) and use this address: ftp://massive.ucsd.edu/MSV000091849/ |
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