PXD041914-2

PXD041914 is an original dataset announced via ProteomeXchange.

Title	Dynamics of de novo heterochromatin assembly and disassembly at replication forks ensures fork stability
Description	Analysis of histone PTM levels in proliferating, quiescent and HU-treated TIG3 fibroblasts. TIG3 fibroblasts were cultured in the absence or presence of HU (600 μM) for at least 6 days, rendering cells quiescent due to contact inhibition or long-term exposure to replication stress, respectively. The dataset contains RAW MS data used for histone PTM quantification presented in Gaggioli et al, 2023 (Fig.1c, Extended Data Fig. 1f and 2c)
HostingRepository	PRIDE
AnnounceDate	2024-10-22
AnnouncementXML	Submission_2024-10-22_05:45:41.237.xml
DigitalObjectIdentifier
ReviewLevel	Peer-reviewed dataset
DatasetOrigin	Original dataset
RepositorySupport	Unsupported dataset by repository
PrimarySubmitter	Andrey Tvardovskiy
SpeciesList	scientific name: Homo sapiens (Human); NCBI TaxID: 9606;
ModificationList	monomethylated residue; acetylated residue
Instrument	TSQ Vantage; Q Exactive

Revision	Datetime	Status	ChangeLog Entry
0	2023-05-01 14:58:31	ID requested
1	2023-05-11 03:56:41	announced
⏵ 2	2024-10-22 05:45:41	announced	2024-10-22: Updated project metadata.

Dataset with its publication pending

submitter keyword: H3K9me,histone PTMs

Nitika Taneja
contact affiliation	Department of Molecular Genetics, Erasmus University Medical Center, Erasmus MC Cancer Institute; Dr. Molewaterplein 40, 3015GD Rotterdam, The Netherlands
contact email	n.taneja@eramsusmc.nl
lab head
Andrey Tvardovskiy
contact affiliation	Institute of Functional Epigenetics, Helmholtz Zentrum München, 85764 Neuherberg, Germany
contact email	tvardovsky.a@gmail.com
dataset submitter

Dataset FTP location NOTE: Most web browsers have now discontinued native support for FTP access within the browser window. But you can usually install another FTP app (we recommend FileZilla) and configure your browser to launch the external application when you click on this FTP link. Or otherwise, launch an app that supports FTP (like FileZilla) and use this address: ftp://ftp.pride.ebi.ac.uk/pride/data/archive/2023/05/PXD041914

PRIDE project URI

• PRIDE
  1. PXD041914
     1. Label: PRIDE project
     2. Name: Dynamics of de novo heterochromatin assembly and disassembly at replication forks ensures fork stability