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PXD041864-1

PXD041864 is an original dataset announced via ProteomeXchange.

Dataset Summary
TitleOchrogaster lunifer setae proteome
DescriptionOchrogaster lunifer (Lepidoptera: Notodontidae) is an Australian processionary caterpillar with detachable urticating setae that have a defensive function. These true setae induce inflammation when they contact human skin, and equine foetal loss syndrome if they are accidentally ingested by gravid horses. We used transcriptomics and proteomics to identify proteins and peptides present in and on urticating setae, which may include toxins that contribute to inflammation and/or foetal loss syndromes. This process identified 37 putative toxins, including multiple homologues of the honeybee venom peptide secapin, and proteins with similarity to odorant binding proteins, arylphorins, and the insect immune modulator Diedel. This work identifies candidate molecules that may contribute to the adverse effects of processionary caterpillar setae on human and animal health.
HostingRepositoryPRIDE
AnnounceDate2024-07-30
AnnouncementXMLSubmission_2024-07-29_16:17:29.129.xml
DigitalObjectIdentifier
ReviewLevelPeer-reviewed dataset
DatasetOriginOriginal dataset
RepositorySupportUnsupported dataset by repository
PrimarySubmitterAndrew Walker
SpeciesList scientific name: Ochrogaster lunifer; NCBI TaxID: 319761;
ModificationListamidated residue
InstrumentTripleTOF 5600
Dataset History
RevisionDatetimeStatusChangeLog Entry
02023-04-27 20:35:37ID requested
12024-07-29 16:17:29announced
Publication List
Walker AA, Perkins LE, Battisti A, Zalucki MP, King GF, Proteome of urticating setae of Ochrogaster lunifer, a processionary caterpillar of medical and veterinary importance, including primary structures of putative toxins. Proteomics, 23(20):e2300204(2023) [pubmed]
10.1002/pmic.202300204;
Keyword List
ProteomeXchange project tag: Toxicoproteomics (B/D-HPP), Biology/Disease-Driven Human Proteome Project (B/D-HPP), Human Proteome Project
submitter keyword: processionary caterpillar
equine amnionitis and foetal loss
Lepidoptera
toxin
Contact List
Glenn King
contact affiliationInstitute for Molecular Biosciences, The University of Queensland
contact emailglenn.king@imb.uq.edu.au
lab head
Andrew Walker
contact affiliationUniversity of Queensland
contact emaila.walker@uq.edu.au
dataset submitter
Full Dataset Link List
Dataset FTP location
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