PXD041822-2

PXD041822 is an original dataset announced via ProteomeXchange.

Title	Proteome-wide adaptation of Lactococcus cremoris after a carbon upshift
Description	Bacteria must adapt their proteome composition to optimize their growth and fitness after an environmental shift. For the lactic acid bacterium Lactococcus cremoris, the shift from galactose to glucose as the main carbon source is associated with large growth rate and physiological changes. This study used protein turnover to investigate the strategies underlying proteome-wide adaptation after a shift from galactose to glucose as the main carbon source for two closely related Lactococcus cremoris strains.
HostingRepository	PRIDE
AnnounceDate	2025-03-17
AnnouncementXML	Submission_2025-03-17_07:18:06.867.xml
DigitalObjectIdentifier
ReviewLevel	Peer-reviewed dataset
DatasetOrigin	Original dataset
RepositorySupport	Unsupported dataset by repository
PrimarySubmitter	Sjef Boeren
SpeciesList	scientific name: Lactococcus lactis subsp. cremoris MG1363; NCBI TaxID: 416870;
ModificationList	S-carboxamidoethyl-L-cysteine; acetylated residue; monohydroxylated residue; deamidated residue
Instrument	Q Exactive HF-X

Revision	Datetime	Status	ChangeLog Entry
0	2023-04-26 03:38:40	ID requested
1	2025-02-17 06:17:46	announced
⏵ 2	2025-03-17 07:18:07	announced	2025-03-17: Updated project metadata.

10.1128/mbio.02990-24;

van Olst B, Boeren S, Vervoort J, Kleerebezem M, elicits immediate initiation of proteome-wide adaptation, coinciding with growth acceleration and pyruvate dissipation switching. mBio, 16(3):e0299024(2025) [pubmed]

submitter keyword: sugar, environmental shift, Lactococcus cremoris, metabolic switch,Protein turnover

Sjef Boeren
contact affiliation	Wageningen University
contact email	sjef.boeren@wur.nl
lab head
Sjef Boeren
contact affiliation	Biochemistry
contact email	sjef.boeren@wur.nl
dataset submitter

Dataset FTP location NOTE: Most web browsers have now discontinued native support for FTP access within the browser window. But you can usually install another FTP app (we recommend FileZilla) and configure your browser to launch the external application when you click on this FTP link. Or otherwise, launch an app that supports FTP (like FileZilla) and use this address: ftp://ftp.pride.ebi.ac.uk/pride/data/archive/2025/02/PXD041822

PRIDE project URI

• PRIDE
  1. PXD041822
     1. Label: PRIDE project
     2. Name: Proteome-wide adaptation of Lactococcus cremoris after a carbon upshift