PXD041775 is an
original dataset announced via ProteomeXchange.
Dataset Summary
Title | G6PD K403 acetylation-dependent PTM |
Description | To identify acetylation-dependent posttranslational modifications (PTMs) of G6PD, site-specifically acetylated and Flag-tagged G6PD was expressed in HEK293T cells by genetically encoding the incorporation of acetylated lysine in response to an in-frame TAG stop codon. K403-acetylated G6PD (sample) and K414-acetylated G6PD (control) were co-expressed with WT Fyn kinase and a catalytically inactive mutant of Fyn (FynDN). G6PD was immunoprecipitated using anti-Flag beads before MS analysis. |
HostingRepository | PRIDE |
AnnounceDate | 2024-10-22 |
AnnouncementXML | Submission_2024-10-22_06:10:03.419.xml |
DigitalObjectIdentifier | |
ReviewLevel | Peer-reviewed dataset |
DatasetOrigin | Original dataset |
RepositorySupport | Unsupported dataset by repository |
PrimarySubmitter | Eyal Arbely |
SpeciesList | scientific name: Homo sapiens (Human); NCBI TaxID: 9606; |
ModificationList | phosphorylated residue; acetylated residue |
Instrument | Q Exactive |
Dataset History
Revision | Datetime | Status | ChangeLog Entry |
0 | 2023-04-24 06:41:43 | ID requested | |
1 | 2023-10-24 12:33:42 | announced | |
2 | 2023-11-14 09:09:47 | announced | 2023-11-14: Updated project metadata. |
⏵ 3 | 2024-10-22 06:10:04 | announced | 2024-10-22: Updated project metadata. |
Publication List
10.1038/s41467-023-41895-2; |
Wu F, Muskat NH, Dvilansky I, Koren O, Shahar A, Gazit R, Elia N, Arbely E, Acetylation-dependent coupling between G6PD activity and apoptotic signaling. Nat Commun, 14(1):6208(2023) [pubmed] |
Keyword List
submitter keyword: Human G6PD, PTM-dependent PTM, acetylation, phosphorylation |
Contact List
Eyal Arbely |
contact affiliation | Department of Chemistry, Ben-Gurion University of the Negev, Israel. |
contact email | arbely@bgu.ac.il |
lab head | |
Eyal Arbely |
contact affiliation | Ben-Gurion University of the Negev |
contact email | arbely@exchange.bgu.ac.il |
dataset submitter | |
Full Dataset Link List
Dataset FTP location
NOTE: Most web browsers have now discontinued native support for FTP access within the browser window. But you can usually install another FTP app (we recommend FileZilla) and configure your browser to launch the external application when you click on this FTP link. Or otherwise, launch an app that supports FTP (like FileZilla) and use this address: ftp://ftp.pride.ebi.ac.uk/pride/data/archive/2023/10/PXD041775 |
PRIDE project URI |
Repository Record List
[ + ]
[ - ]
- PRIDE
- PXD041775
- Label: PRIDE project
- Name: G6PD K403 acetylation-dependent PTM