PXD041762-1
PXD041762 is an original dataset announced via ProteomeXchange.
Dataset Summary
Title | PROTEOMICS EVOLUTION FROM ACUTE TO POST-COVID-19 CONDITION |
Description | We performed longitudinal plasma proteomics analysis and determined absolute protein levels in a Canadian cohort (n=74) at admission day to hospital for acute COVID-19 and at 3 and 6 months after diagnosis of acute COVID-19. We measured plasma protein on a triple quadrupole mass spectrometer operated in multiple reaction monitoring mode and used internal standards to deduce protein absolute concentrations. We used a validated panel of 269 surrogate heavy labeled peptides. We also measured % predicted forced vital capacity (FVC, %) and diffusing capacity of the lungs for carbon monoxide (DLCO, %) by routine pulmonary function testing. We did functional enrichment and pathway analyses and determined proteins that were increased or decreased from hospital admission to 3-months and 6-months, compared females to males and determined associations of proteins with FVC% and DLCO%. |
HostingRepository | PRIDE |
AnnounceDate | 2024-01-26 |
AnnouncementXML | Submission_2024-01-26_08:01:48.559.xml |
DigitalObjectIdentifier | |
ReviewLevel | Peer-reviewed dataset |
DatasetOrigin | Original dataset |
RepositorySupport | Unsupported dataset by repository |
PrimarySubmitter | Yassene Mohammed |
SpeciesList | scientific name: Homo sapiens (Human); NCBI TaxID: 9606; |
ModificationList | No PTMs are included in the dataset |
Instrument | 6490 Triple Quadrupole LC/MS |
Dataset History
Revision | Datetime | Status | ChangeLog Entry |
---|---|---|---|
0 | 2023-04-24 02:01:03 | ID requested | |
⏵ 1 | 2024-01-26 08:01:49 | announced |
Publication List
10.1021/acs.jproteome.3c00324; |
Mohammed Y, Tran K, Carlsten C, Ryerson C, Wong A, Lee T, Cheng MP, Vinh DC, Lee TC, Winston BW, Sweet D, Boyd JH, Walley KR, Haljan G, McGeer A, Lamontagne F, Fowler R, Maslove D, Singer J, Patrick DM, Marshall JC, Murthy S, Jain F, Borchers CH, Goodlett DR, Levin A, Russell JA, Proteomic Evolution from Acute to Post-COVID-19 Conditions. J Proteome Res, 23(1):52-70(2024) [pubmed] |
Keyword List
submitter keyword: COVID-19, restrictive lung disease, Post-COVID-19 condition, targeted proteomics |
Contact List
Yassene Mohammed | |
---|---|
contact affiliation | Center for Proteomics and Metabolomics Leiden University Medical Center |
contact email | y.mohammed@lumc.nl |
lab head | |
Yassene Mohammed | |
contact affiliation | LUMC/UVIC |
contact email | y.mohammed@lumc.nl |
dataset submitter |
Full Dataset Link List
Dataset FTP location NOTE: Most web browsers have now discontinued native support for FTP access within the browser window. But you can usually install another FTP app (we recommend FileZilla) and configure your browser to launch the external application when you click on this FTP link. Or otherwise, launch an app that supports FTP (like FileZilla) and use this address: ftp://ftp.pride.ebi.ac.uk/pride/data/archive/2024/01/PXD041762 |
PRIDE project URI |
Repository Record List
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