PXD041677-1

PXD041677 is an original dataset announced via ProteomeXchange.

Dataset Summary

Title	Mechanism of recovery following human stem cell-derived extracellular vesicle treatment to cerebral ischemia
Description	Characterization of hMSC cell and EV revealed that hypoxia preconditioning upregulated 41 expression of metabolic proteins related to HIF signaling, neurogenesis and EV biogenesis.
HostingRepository	PRIDE
AnnounceDate	2025-07-21
AnnouncementXML	Submission_2025-07-20_17:04:04.954.xml
DigitalObjectIdentifier	https://dx.doi.org/10.6019/PXD041677
ReviewLevel	Peer-reviewed dataset
DatasetOrigin	Original dataset
RepositorySupport	Supported dataset by repository
PrimarySubmitter	li sun
SpeciesList	scientific name: Homo sapiens (Human); NCBI TaxID: 9606;
ModificationList	monohydroxylated residue; iodoacetamide derivatized residue
Instrument	Q Exactive HF

Dataset History

Revision	Datetime	Status	ChangeLog Entry
0	2023-04-20 03:03:49	ID requested
⏵ 1	2025-07-20 17:04:05	announced

Publication List

10.6019/PXD041677;
10.1002/jex2.70063;
Helsper S, Sun L, Jeske R, Liu C, Athey J, Yuan X, Grant SC, Li Y, Cargo Analysis and MRI-Based Therapeutic Assessment of Iron Oxide Labelled Extracellular Vesicles of Hypoxia Human Stem Cells in Ischemic Stroke. J Extracell Biol, 4(7):e70063(2025) [pubmed]

10.6019/PXD041677;

10.1002/jex2.70063;

Helsper S, Sun L, Jeske R, Liu C, Athey J, Yuan X, Grant SC, Li Y, Cargo Analysis and MRI-Based Therapeutic Assessment of Iron Oxide Labelled Extracellular Vesicles of Hypoxia Human Stem Cells in Ischemic Stroke. J Extracell Biol, 4(7):e70063(2025) [pubmed]

Keyword List

submitter keyword: human mesenchymal stem cells
extracellular vesicles
hypoxia
ischemia

submitter keyword: human mesenchymal stem cells

extracellular vesicles

hypoxia

ischemia

Contact List

Li Sun
contact affiliation	FSU COllege of Medicine Tallahassee, FL 32309, USA
contact email	li.sun@med.fsu.edu
lab head
li sun
contact affiliation	Florida State University
contact email	li.sun@med.fsu.edu
dataset submitter

Full Dataset Link List

Dataset FTP location NOTE: Most web browsers have now discontinued native support for FTP access within the browser window. But you can usually install another FTP app (we recommend FileZilla) and configure your browser to launch the external application when you click on this FTP link. Or otherwise, launch an app that supports FTP (like FileZilla) and use this address: ftp://ftp.pride.ebi.ac.uk/pride/data/archive/2025/07/PXD041677
PRIDE project URI

Dataset FTP location
NOTE: Most web browsers have now discontinued native support for FTP access within the browser window. But you can usually install another FTP app (we recommend FileZilla) and configure your browser to launch the external application when you click on this FTP link. Or otherwise, launch an app that supports FTP (like FileZilla) and use this address: ftp://ftp.pride.ebi.ac.uk/pride/data/archive/2025/07/PXD041677

PRIDE project URI

Repository Record List

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